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Displaying results 3821 - 3830 of 10000 in total
  1. Drug

    Salafibrate

    go.drugbank.com/drugs/DB20767
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Salafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Salafibrate is a small molecule drug.

  2. Drug

    Elarofiban anhydrous

    go.drugbank.com/drugs/DB21212
    Experimental

    The usage of the INN stem '-fiban' in the name indicates that Elarofiban anhydrous is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist). … Elarofiban anhydrous is a small molecule drug.

  3. Drug

    Lifibrate

    go.drugbank.com/drugs/DB21399
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Lifibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Lifibrate is a small molecule drug.

  4. Drug

    Chloramphenicol succinate

    go.drugbank.com/drugs/DB07565
    Approved

    Chloramphenicol succinate is an ester prodrug of [chloramphenicol].[A192987] Chloramphenicol is a bacteriostatic antibiotic. … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias.

  5. Drug

    Bilastine

    go.drugbank.com/drugs/DB11591
    Approved

    Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.

    Categories: Antihistamines for Systemic Use
  6. Drug

    Hyaluronidase (human recombinant)

    go.drugbank.com/drugs/DB06205
    ApprovedInvestigational

    [A4033] Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. … [A199026] Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue.

  7. Target

    Prostaglandin E synthase 3

    go.drugbank.com/bio_entities/BE0002480
    TargetHumans

    Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-depende...

    Synonyms: Progesterone receptor complex p23
  8. Target

    Proteasome subunit alpha type-2

    go.drugbank.com/bio_entities/BE0003911
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)

    Synonyms: Multicatalytic endopeptidase complex subunit C3
  9. Target

    Proteasome subunit beta type-7

    go.drugbank.com/bio_entities/BE0003920
    TargetHumans

    Within the 20S core complex, PSMB7 displays a trypsin-like activity … Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.

    Synonyms: Multicatalytic endopeptidase complex chain Z
  10. Drug

    Mefloquine

    go.drugbank.com/drugs/DB00358
    Approved

    [L30623] Mefloquine, commonly known as Lariam, is an antimalarial drug used for the prevention and treatment of malaria caused by infection with Plasmodium vivax and Plasmodium falciparum. … Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world.

    Synonyms: .-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, (R*,S*)-(±)-, [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol