Search

Displaying results 3831 - 3840 of 10000 in total
  1. Target

    Transcription factor p65

    go.drugbank.com/bio_entities/BE0005551
    TargetHumans

    Besides its activity as a direct transcriptional activator, it is also able to modulate promoters accessibility to transcription factors and thereby indirectly regulate gene expression. … Essential for cytokine gene expression in T-cells (PubMed:15790681). The NF-kappa-B homodimeric RELA-RELA complex appears to be involved in invasin-mediated activation of IL-8 expression.

    Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
  2. Target

    Ubiquitin-conjugating enzyme E2 T

    go.drugbank.com/bio_entities/BE0019778
    TargetHumans

    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fan...

    Synonyms: Cell proliferation-inducing gene 50 protein
  3. Drug

    Tabalumab

    go.drugbank.com/drugs/DB11657
    Investigational

    Tabalumab has been used in trials studying the treatment of Autoimmune Disease, Rheumatoid Arthritis, Kidney Failure, Chronic, Connective Tissue Disease, and Systemic Lupus Erythematosus, among others.

    Categories: B-Cell Activating Factor, antagonists & inhibitors
  4. Drug

    Eprenetapopt

    go.drugbank.com/drugs/DB11684
    Investigational

    Eprenetapopt has been used in trials studying the treatment of Prostatic Neoplasms, Hematologic Neoplasms, and Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53.

    Synonyms: 1-Azabicyclo(2.2.2)octan-3-one, 2-(hydroxymethyl)-2-(methoxymethyl)-, 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
  5. Drug

    Astodrimer

    go.drugbank.com/drugs/DB11854
    Investigational

    Astodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Vatiquinone

    go.drugbank.com/drugs/DB11917
    Investigational

    Vatiquinone has been investigated for the treatment and prevention of Retinopathy, Rett Syndrome, Genetic Disease, Noise-induced Hearing Loss, and Methylmalonic Aciduria and Homocystinuria,Cblc Type.

  7. Drug

    Sapitinib

    go.drugbank.com/drugs/DB12183
    Investigational

    Sapitinib has been used in trials studying the treatment and basic science of Neoplasms, Breast Cancer, Breast Neoplasms, Metastatic Cancer, and Metastatic Breast Cancer, among others.

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Polmacoxib

    go.drugbank.com/drugs/DB12399
    Investigational

    Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of

    Categories: COX-2 Inhibitors, Heterocyclic Compounds, 1-Ring
  9. Drug

    Theanine

    go.drugbank.com/drugs/DB12444
    Investigational

    Theanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).

    Synonyms: N(5)-ethyl-L-glutamine, N-ethyl-L-glutamine
  10. Drug

    Ditiocarb

    go.drugbank.com/drugs/DB02520
    Investigational

    A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.

    Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A Inhibitors