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Amilomotide
go.drugbank.com/drugs/DB05150InvestigationalCAD106 is an immunotherapeutic product in development for the treatment of Alzheimer's disease. It is designed to induce antibodies against the beta-amyloid-protein that inhibit the formation of plaques in the brain of Alzheimer's diseas...
Nuclear factor NF-kappa-B
go.drugbank.com/bio_entities/BE0004903TargetHumansNF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as in...
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Betula pendula tar oil
go.drugbank.com/drugs/DB11361ApprovedNutraceutical[L2870] Betula pendula tar oil has been approved for its utilization in over-the-counter product combinations by Health Canada.
Neon
go.drugbank.com/drugs/DB11589ApprovedOther clinical applications of neon, such as a radiotherapy in various cancers [A32763], have been studied. … Neon may be used in the clinical setting as a diagnostic tracer gas in a gas analyzer for a lung diffusion test.
Calcium gluconate
go.drugbank.com/drugs/DB11126ApprovedInvestigationalVet approvedHydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). … Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate.
Synonyms: D-gluconic acid, calcium salt (2:1)Mixtures: Formula 9 Tab, FOSFO KALSIYUM GRANULE, 75 GAbemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalAbemaciclib has been used in trials studying the treatment of melanoma, lymphoma, neoplasm, solid tumor, and glioblastoma. … Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VERZENIO® 100 MG, VERZENIO® 150 MGHyaluronidase (human recombinant)
go.drugbank.com/drugs/DB06205ApprovedInvestigational[A199026] Hyaluronidase has been used in surgical settings for at least the past 60 years to improve the diffusion of local anesthetics. … A purified preparation of the enzyme recombinant human hyaluronidase.
Zotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawn[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's.[A31857] Zotepine was never approved by the FDA. … Zotepine, with the formula (2-chloro-11-(2-dimethyl-amino-ethoxy)-dibenzo thiepin, is a neuroleptic drug. It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: ZOLEPTIL © 50 MG TABLETAS RECUBIERTAS.Tenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigational[A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir disoproxil. … [A178327] Tenofovir alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388,L6277,L6280,L6283] and prevent HIV-1 infections.
Mixtures: GENVOYA ® TABLETAS RECUBIERTAS, DESCOVY® 200MG/10MG TABLETAS RECUBIERTASCategories: Vitamin B Complex, Cytochrome P-450 SubstratesDipyrithione
go.drugbank.com/drugs/DB11327Approved[A32829] Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum antitumor activity, which suggests a potential basis for an anticancer drug development. … [L2611] It is currently used as a pesticide, and not used in any FDA approved drug products.
Categories: Heterocyclic Compounds, 1-Ring