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Borage oil

eczema, seborrheic dermatitis, and neurodermatitis as well as other inflammatory, cardiovascular and endocrine disorders, although its clinical efficacy and long-term effects are not fully elucidated yet

Sebelipase alfa

It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion Pharmaceuticals).[L39337,L39342]

Siltuximab

It is administered as a 1 hour intravenous infusion every 3 weeks.

Shark liver oil

The potential benefit of shark oil has been experimented in different therapeutic implications, where it is claimed to improve immune responses and exert an antitumor activity.

Zenocutuzumab

[L51963] It works to attenuate aberrant cancer cell growth caused by genomic rearrangements involving the neuregulin 1 gene (NRG1), which is an oncogenic driver.

Oxcarbazepine

[L8627,L8630,L8633] It is a structural derivative of [carbamazepine][A186101] and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate in the blood

Pam2csk4

Y-27632

It inhibits calcium sensitization to affect smooth muscle relaxation.

Aganirsen

Aganirsen is under investigation in clinical trial NCT02947867 (Trial of Aganirsen in iCRVO Patients at Risk of Developing NVG).

CTR-107

It is being investigated for the treatment of familial exudative vitreoretinopathy.