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Desmopressin
go.drugbank.com/drugs/DB00035ApprovedInvestigationalIt is considered a first-line therapy for central diabetes insipidus but is ineffective in patients with nephrogenic diabetes insipidus, where the kidneys are non-responsive to the hormone [A275458, L56105 … Additionally, it serves as a critical hematologic agent for the management of mild hemophilia A and von Willebrand disease (Type I) by transiently increasing levels of clotting factors [A31662, A275458
Products: Nu-desmopressin SprayAcetylcarnitine
go.drugbank.com/drugs/DB08842ApprovedInvestigationalAcetylcarnitine can be synthesized, but it is also naturally found in adequate amounts in healthy humans. … Acetylcarnitine is an investigational drug in the United states, Italy, United Kingdom, China, Israel, and Norway, and it is approved in Italy, Portugal, Argentina, Chile, Philippines, Australia, and India
Enalapril
go.drugbank.com/drugs/DB00584ApprovedInvestigationalVet approvedIt was developed from a targeted research programmed using molecular modelling. … Commonly marketed under the trade name Vasotec, enalapril was first approved by the FDA in 1985 for the management of hypertension, heart failure, and asymptomatic left ventricular dysfunction.
Synonyms: (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline, 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl esterProducts: Nu-enalaprilDiclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation from a variety of causes. … Diclofenac was first approved by the FDA in July 1988 under the trade name Voltaren, marketed by Novartis (previously Ciba-Geigy).[L7360]
International brands: Nu-DicloProducts: Nu-diclo Rapide, Nu-diclo SR - Srt 75mgImdevimab
go.drugbank.com/drugs/DB15940ApprovedInvestigational[L23539] This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. … [L23524] In November 2021, the same indication was approved by the EMA.
Haloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigationalHowever, these findings contradict the findings from studies in vitro with human liver microsomes and from drug interaction studies in vivo. … haloperidol to lower-potency first-generation antipsychotics such as [DB00477], [DB01624], [DB00623], and [DB01403], haloperidol typically demonstrates the least amount of side effects within this class, but
Products: Nu-haloperidolOxamniquine
go.drugbank.com/drugs/DB01096ApprovedOxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. … An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp.
Perindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalPerindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration....
Mixtures: BIPRETERAX N 5MG/1.25MG, BIPRETERAX N 5MG/1.25MGProducts: Nb-perindoprilSulopenem etzadroxil
go.drugbank.com/drugs/DB16335ApprovedInvestigational[L51858] It is administered in combination with [probenecid] in order to increase antibiotic exposure.[L51768] … [L51768] Sulopenem etzadroxil was approved by the FDA in October 2024 for the treatment of uncomplicated urinary tract infections.
Tenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigational[T239] Tenofovir alafenamide is an alanine ester form characterized for presenting low systemic levels but high intracellular concentration. … Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when compared to the counterpart [tenofovir disoproxil].