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Histamine
go.drugbank.com/drugs/DB05381ApprovedInvestigationalIt is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. … A depressor amine derived by enzymatic decarboxylation of histidine.
Synonyms: 1H-Imidazole-4-ethanamine, 5-imidazoleethylamineMixtures: Histamine DHCl 0.10 Percent and Menthol 2 Percent, Md Science CannabidiolVisometin cation
go.drugbank.com/drugs/DB18089InvestigationalSynonyms: (10-(4,5-dimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl)triphenylphosphonium, Phosphonium, (10-(4,5-dimethyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl)triphenyl-Vimseltinib
go.drugbank.com/drugs/DB17520ApprovedInvestigationalVimseltinib is a small molecule kinase inhibitor targeting colony-stimulating factor 1 receptor (CSF1R). … in a lower risk of off-target effects, including hepatotoxicity.
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 3-methyl-2-((1-methylethyl)amino)-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)-4-pyridinyl)oxy)-2-pyridinyl)-4(3h)-pyrimidinone, 4(3h)-pyrimidinone, 3-methyl-2-((1-methylethyl)amino)-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)-4-pyridinyl)oxy)-2-pyridinyl)-Thymidine
go.drugbank.com/drugs/DB04485ApprovedInvestigationaltoxicity of established anti-metabolite chemotherapeutic agents, such as 5-Fluorouracil (FU), Methotrexate (MTX), and Cytosine arabinoside (ara-C). … Thymidine is a naturally occurring deoxyribonucleoside that is a crucial component of the DNA salvage pathway and a building block for DNA synthesis.
Categories: Heterocyclic Compounds, 1-Ring, Nucleic Acids, Nucleotides, and NucleosidesSynonyms: MT-1621 COMPONENT 2'-DEOXYTHYMIDINE, 1-(2-Deoxy-?-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedioneDarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalDarifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. … It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments.
Categories: Heterocyclic Compounds, 1-Ring, Genito Urinary System and Sex HormonesSynonyms: (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamideOxytetracycline
go.drugbank.com/drugs/DB00595ApprovedInvestigationalVet approvedA tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Mixtures: HEKSA 30 MG/G + 10000 I.U./G MERHEM, POLIMISIN GÖZ MERHEMI, 3,5 GCategories: Alimentary Tract and Metabolism, Genito Urinary System and Sex HormonesFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigational[L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones … Febuxostat is a non-purine xanthine oxidase (XO) inhibitor.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesSynonyms: 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acidOxacillin
go.drugbank.com/drugs/DB00713ApprovedInvestigationalAn antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (5-methyl-3-phenyl-4-isoxazolyl)penicillinAceprometazine
go.drugbank.com/drugs/DB01615ExperimentalAceprometazine is a is a drug with neuroleptic and anti-histamine properties.
Synonyms: 10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketoneCategories: Heterocyclic Compounds, 3-Ring