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Displaying results 381 - 390 of 8010 in total
  1. Drug

    Carmustine

    go.drugbank.com/drugs/DB00262
    ApprovedInvestigational

    (From Merck Index, 11th ed) … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).

    Products: Carmustine for Injection USP, BiCNU-100MG (CARMUSTINE FOR INJECTION USP 100MG) & DEHYDRATED ALCOHOL INJECTION USP AS A COMBIPACK
  2. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    [A204083] In May 2003, bortezomib became the first anticancer proteasome inhibitor that was approved by the FDA under the trade name VELCADE.

    Products: Retrox 3.5mg Powder for Solution for Injection, BORTESUN POWDER FOR SOLUTION FOR INJECTION 3.5 mg
  3. Drug

    Nivolumab

    go.drugbank.com/drugs/DB09035
    ApprovedInvestigational

    [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability. … [A35203] It was developed by Bristol Myers Squibb.[L12129] Nivolumab was granted FDA approval on 22 December 2014.

    Products: OPDIVO CONCENTRATE FOR SOLUTION FOR INFUSION 10 MG/ML, Opdivo 10mg/ml, Concentrate for solution for infusion
  4. Drug

    Eptinezumab

    go.drugbank.com/drugs/DB14040
    ApprovedInvestigational

    [F94,A33105,A33106,A33108] It was approved by the FDA in February 2020 for the preventive treatment of migraine headaches in adults.[L12318] … Eptinezumab is a fully-humanized IgG1 antibody manufactured using yeast (_Pichia pastoris_) and developed by Lundbeck Seattle Biopharmaceuticals.

    Products: VYEPTI CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/ML, Vyepti® 100 mg/mL concentrate for solution for infusion
  5. Drug

    Cefepime

    go.drugbank.com/drugs/DB01413
    ApprovedInvestigational

    [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Cefevon powder for solution for injection 2g/vial, ROXIPIME POWDER FOR SOLUTION FOR INJECTION 2G/VIAL
  6. Drug

    Omeprazole

    go.drugbank.com/drugs/DB00338
    ApprovedInvestigationalVet approved

    Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. … These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid.

    Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Products: SOLCER POWDER FOR SOLUTION FOR INFUSION 40mg/vial, omepiva 40mg Powder and Solvent for Solution for Injection
  7. Drug

    Testosterone undecanoate

    go.drugbank.com/drugs/DB13946
    ApprovedInvestigational

    [L35970,L8932,L41355] Testosterone is a critical male hormone that is responsible for the normal growth and development of the male sex organs and for the maintenance of secondary sex characteristics … Male hypogonadism, resulting from insufficient testosterone secretion, can result symptoms and signs of testosterone deficiency, such as decreased libido, erectile dysfunction, and loss of muscle and bone

    Products: NEBIDO 1000MG SOLUTION FOR INJECTION
  8. Drug

    Thimerosal

    go.drugbank.com/drugs/DB11590
    Approved

    Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used...

    Synonyms: [(o-carboxyphenyl)thio]ethylmercury sodium salt, ethylmercurithiosalicylic acid sodium saltCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Elosulfase alfa

    go.drugbank.com/drugs/DB09051
    ApprovedInvestigational

    It was approved by the FDA in 2014 for the treatment of Morquio syndrome. Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™.

    Products: Vimizim 1mg/ml Concentrate for Solution for Infusion
  10. Drug

    Azacitidine

    go.drugbank.com/drugs/DB00928
    ApprovedInvestigational

    It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. … [A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved by the FDA in September 2020.[L35335]

    Products: Azacitidine For, Vidaza powder for suspension for injection 100mg/vial