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Displaying results 3911 - 3920 of 10000 in total
  1. Drug

    Imexon

    go.drugbank.com/drugs/DB05003
    Investigational

    Imexon is currently being studied for the treatment of pancreatic, lung, breast, prostate, melanoma, and multiple myeloma cancers. It belongs to the family of drugs called cyanoaziridine derivatives. … Imexon is a cyanoaziridine derivative. Imexon is a thiol-binding small molecule which induces mitochondrial oxidation, a loss of membrane potential and cytochrome C, leading to apoptosis.

  2. Drug

    Rimexolone

    go.drugbank.com/drugs/DB00896
    ApprovedWithdrawn

    Rimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.

    Categories: Corticosteroids for Systemic Use, Plain
  3. Drug

    Cretostimogene grenadenorepvec

    go.drugbank.com/drugs/DB05148
    Investigational

    CG0070 is investigated in clinical trials for treating bladder cancer. CG0070 is a solid. … CG0070, an oncolytic virus therapy with specificity for multiple cancers, has been evaluated in numerous preclinical studies.

  4. Drug

    CT-011

    go.drugbank.com/drugs/DB05916
    Investigational

    CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. … It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.

  5. Drug

    Cyanamide

    go.drugbank.com/drugs/DB02679
    Experimental

    The citrated calcium salt is used in the treatment of alcoholism. [PubChem] … A cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide.

  6. Drug

    Perflenapent

    go.drugbank.com/drugs/DB11625
    ApprovedInvestigationalWithdrawn

    Dodecafluoropentane is also known as perfluoropentane or perflenapent.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Paquinimod

    go.drugbank.com/drugs/DB13118
    Investigational

    Paquinimod is developed for the treatment of SLE (Systemic Lupus Erythematosus), which is an autoimmune disease. … Current treatments of SLE are NSAID (nonsteroidal anti-inflammatory drugs), corticosteroids, antimalarians or cytotoxic drugs like for example Cyclophosphamide.

  8. Drug

    Maxy-G34

    go.drugbank.com/drugs/DB05718
    Investigational

    It is being developed by Maxygen, Inc. for the treatment of chemotherapy-induced neutropenia. … , while Neulasta has a single 20 Kd PEG group attached at the N terminal end of the wild type G-CSF protein.

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Pancrelipase protease

    go.drugbank.com/drugs/DB11066
    ApprovedInvestigational

    [A32742, L2543] The pancrelipase mixture, including pancrelipase protease, was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.[L2510] … Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.

    Mixtures: KREON MIKRO 5000 IU MINIMIKROSFER,
  10. Drug

    Resveratrol

    go.drugbank.com/drugs/DB02709
    Investigational

    It exists as cis-(Z) and trans-(E) isomers. The trans- form can undergo isomerisation to the cis- form when heated or exposed to ultraviolet irradiation. In a 2004 issue of Science, Dr. … Sinclair of Harvard University said resveratrol is not an easy molecule to protect from oxidation. It has been claimed that it is readily degraded by exposure to light, heat, and oxygen.

    Mixtures: Co-Balamin, Co-VeratrolCategories: Compounds used in a research, industrial, or household setting