Search
MK-0731
go.drugbank.com/drugs/DB08037InvestigationalMK-0731 is a kinesin spindle protein inhibitor and antineoplastic agent.
Zucapsaicin
go.drugbank.com/drugs/DB09120ApprovedWithdrawnZucapsaicin was approved by the Health Canada in 2010 as topical cream marketed under the brand name Zuacta but currently not FDA-approved. … These conditions include herpes simplex (HSV) infections, cluster headaches, migraine, and osteoarthritis of the knee.
Categories: Capsaicin and Similar Agents, Topical Products for Joint and Muscular PainVusolimogene oderparepvec
go.drugbank.com/drugs/DB23008ApprovedInvestigational[L64061] The virus is engineered to express a fusogenic glycoprotein derived from gibbon ape leukemia virus (GALV-GP-R–) and human granulocyte-macrophage colony-stimulating factor (GM-CSF), and has its … killing and GM-CSF promoting dendritic cell and monocyte activation to drive an anti-tumor immune response.
Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsOlodaterol
go.drugbank.com/drugs/DB09080ApprovedInvestigationalOlodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs. … relaxation and bronchodilation.
Categories: olodaterol and tiotropium bromideNeurocognitive Disorders
go.drugbank.com/conditions/DBCOND0064252Drugs: ZuclopenthixolSynonyms: Dementia and Amnestic ConditionsDP-VPA
go.drugbank.com/drugs/DB05821InvestigationalDP-VPA is D-Pharm's proprietary lipid modified version of valproic acid (VPA) that demonstrate that DP-VPA is well-tolerated in patients with resistant epilepsy and has a marked effect on reducing seizure
Droxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalThe racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. … Chelsea Therapeutics obtained orphan drug status (ODS) for L-DOPS in the U.S. for NOH, and that of which associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is
Categories: Epinephrine and similars, Adrenergic and Dopaminergic AgentsVandetanib
go.drugbank.com/drugs/DB05294ApprovedInvestigationalVandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types. … On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.
Categories: Antineoplastic and Immunomodulating AgentsBexarotene
go.drugbank.com/drugs/DB00307ApprovedInvestigationalBexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Categories: Antineoplastic and Immunomodulating AgentsAmdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnIt is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.