Search

Displaying results 3961 - 3970 of 10000 in total
  1. Pathway

    Joubert Syndrome

    smpdb.ca/view/SMP0000582
    Disease

    Many different gene mutations are responsible for Joubert syndrome, all of the proteins created from these genes affecting the cilia that are found on the cell surface. … The symptoms affect a variety of body parts in the patient, including apnea, ataxia brought on by hypotonia, abnormal eye movements and intellectual disability.

    Drugs: ATP · Calcium · Magnesium cation · Inositol
    Enzymes: Activating molecule in BECN1-regulated autophagy protein 1
  2. Pathway

    Joubert Syndrome

    smpdb.ca/view/SMP0125809
    Disease

    Many different gene mutations are responsible for Joubert syndrome, all of the proteins created from these genes affecting the cilia that are found on the cell surface. … The symptoms affect a variety of body parts in the patient, including apnea, ataxia brought on by hypotonia, abnormal eye movements and intellectual disability.

    Drugs: ATP · Calcium · Magnesium cation · Inositol
    Enzymes: Activating molecule in BECN1-regulated autophagy protein 1
  3. Drug

    AZD3409

    go.drugbank.com/drugs/DB04893
    Experimental

    AZD3409 is a farnesyl-transferase inhibitor (FAR) indicated for the treatment of solid tumors. Phase I trials were initiated January 2003, and were ongoing as of February 2004.

  4. Drug

    Plicamycin

    go.drugbank.com/drugs/DB06810
    ApprovedWithdrawn

    It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued plicamycin in 2000. … Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Methoxyamine

    go.drugbank.com/drugs/DB06328
    Investigational

  6. Drug

    Gabapentin enacarbil

    go.drugbank.com/drugs/DB08872
    Approved

    Gabapentin enacarbil is marketed under the name Horizant. It is a prodrug of gabapentin, and indicated in adults for the treatment of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).

  7. Drug

    trans NV-04

    go.drugbank.com/drugs/DB05843
    Experimental

    trans NV-04 is a cardiovascular drug which shows a significant reduction in blood pressure and arterial stiffness.

    Synonyms: trans NV-04
  8. Drug

    WU-NK-101

    go.drugbank.com/drugs/DB18350
    Investigational

    WU-NK-101 is an allogeneic CD3-depleted, CD56-enriched activated natural killer-cell product

  9. Drug

    Tranylcypromine

    go.drugbank.com/drugs/DB00752
    ApprovedInvestigational

    It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). … Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring.

    Categories: Antidepressive Agents Indicated for Depression, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  10. Drug

    Creatine

    go.drugbank.com/drugs/DB00148
    ApprovedInvestigationalNutraceutical

    An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.

    Synonyms: N-methyl-N-guanylglycine, N-carbamimidoyl-N-methylglycine