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Metampicillin
go.drugbank.com/drugs/DB13836ExperimentalIt is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the stomach.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseRufinamide
go.drugbank.com/drugs/DB06201ApprovedRufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy.
J147
go.drugbank.com/drugs/DB13957Experimental[A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesMefloquine
go.drugbank.com/drugs/DB00358Approved[L30623] Mefloquine, commonly known as Lariam, is an antimalarial drug used for the prevention and treatment of malaria caused by infection with Plasmodium vivax and Plasmodium falciparum. … Individuals at the highest risk for malaria are those in disease naïve populations, children under age 5, refugees in Central and Eastern Africa, nonimmune civilian and military travelers, pregnant women
Cortisone
go.drugbank.com/drugs/DB14681InvestigationalIt has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive.
Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainLigelizumab
go.drugbank.com/drugs/DB11856InvestigationalInitial trials of ligelizumab suggest a greater efficacy over its predecessor for the treatment of CSU.[A242367] … [A242292] Ligelizumab is currently under investigation for the treatment of chronic spontaneous urticaria (CSU), an autoimmune-driven inflammatory condition.
Lemuteporfin
go.drugbank.com/drugs/DB04980InvestigationalIt is intended for the treatment of beign prostatic hyperplasia.
Categories: Heterocyclic Compounds with 4 or More RingsCXD101
go.drugbank.com/drugs/DB16182InvestigationalCXD101 is under investigation in clinical trial NCT03873025 (A Study of CXD101 in Combination With Pembrolizumab for Relapsed or Refractory Diffuse Large B-cell Lymphoma).
Depatuxizumab mafodotin
go.drugbank.com/drugs/DB11731InvestigationalDepatuxizumab/Denintuzumab mafodotin has been used in trials studying the treatment of Lymphoma, Gliosarcoma, Glioblastoma, Malignant Glioma, Squamous Cell Tumors, and Glioblastoma Multiforme.