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Vilobelimab
go.drugbank.com/drugs/DB16416ApprovedInvestigationalIt consists of mouse anti-human complement factor 5a (C5a) monoclonal binding sites (variable regions of heavy and light chain regions) and human gamma 4 heavy chain and light kappa chain constant regions … Vilobelimab is a chimeric monoclonal immunoglobulin G4 (IgG4) antibody that binds to the soluble form of human C5a with high affinity.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsAluminium
go.drugbank.com/drugs/DB01370ApprovedInvestigationalWithdrawnA metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.
Categories: Aluminum and magnesium containing antacidsalpha-Linolenic acid
go.drugbank.com/drugs/DB00132ApprovedInvestigationalNutraceuticalWithdrawnIt is a component of many common vegetable oils and is important to human nutrition.
Lisocabtagene maraleucel
go.drugbank.com/drugs/DB16582ApprovedInvestigationalLisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to [brexucabtagene autoleucel] and [axicabtagene ciloleucel]. … [A228493] Lisocabtagene maraleucel was granted FDA approval on 5 February 2021 [L31583] and EC approval on 5 April 2022.[L42210] It was later granted Health Canada approval on 6 May 2022.
Categories: Antineoplastic cell and gene therapy, Antineoplastic and Immunomodulating AgentsAmifampridine
go.drugbank.com/drugs/DB11640ApprovedFirdapse (amifampridine) was formally approved by the US FDA for the treatment of adults with LEMS as recently as November of 2018 [L4819]. … It was demonstrated in clinical studies involving healthy volunteers that the pharmacokinetics and systemic exposure to amifampridine is affected by the genetic differences in N-acetyl-transferase (NAT
Chenodeoxycholic acid
go.drugbank.com/drugs/DB06777ApprovedInvestigationalIt works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. … Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body.
Categories: Bile Acids and Salts, Bile and Liver TherapyTianeptine
go.drugbank.com/drugs/DB09289InvestigationalAsia (including Singapore) and Latin America as “Stablon” and “Tatinol” but it is not available in Australia, Canada, New Zealand, the U.K. or the U.S. … Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s [L2946].
Oxyphenonium
go.drugbank.com/drugs/DB00219ApprovedIt is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. [PubChem]
Categories: Alimentary Tract and MetabolismNomegestrol acetate
go.drugbank.com/drugs/DB13981ApprovedNomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Mixtures: FEMIDEN® 1.5 MG/2.5MG TABLETAS RECUBIERTASCategories: Combination Contraceptives (with Estrogen and derivatives)Quinidine barbiturate
go.drugbank.com/drugs/DB01346ApprovedThe administration of quinidine derivatives helps to observe various skin and mucosal reactions. … A papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and at reintroduction.(PMID: 9739909)