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Killer cell immunoglobulin-like receptor 3DL2
go.drugbank.com/bio_entities/BE0010849TargetHumansReceptor on natural killer (NK) cells and T cells for MHC class I molecules (PubMed:24018270, PubMed:28636952). Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions (PubMed:24018270). A...
Polypeptides: Killer cell immunoglobulin-like receptor 3DL2Killer cell immunoglobulin-like receptor 2DL1
go.drugbank.com/bio_entities/BE0010669TargetHumansReceptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis
Polypeptides: Killer cell immunoglobulin-like receptor 2DL1Killer cell immunoglobulin-like receptor 2DL3
go.drugbank.com/bio_entities/BE0010665TargetHumansReceptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis
Polypeptides: Killer cell immunoglobulin-like receptor 2DL3High affinity immunoglobulin epsilon receptor subunit gamma
go.drugbank.com/bio_entities/BE0000049TargetHumansAs a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells.
Polypeptides: High affinity immunoglobulin epsilon receptor subunit gammaLeukocyte immunoglobulin-like receptor subfamily B member 1
go.drugbank.com/bio_entities/BE0010562TargetHumansRecognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:16455647, PubMed:28636952). Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. … Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (PubMed:16455647).
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily B member 1Synonyms: Immunoglobulin-like transcript 2, Leukocyte immunoglobulin-like receptor 1High affinity immunoglobulin gamma Fc receptor I
go.drugbank.com/bio_entities/BE0000710TargetCarrierHumansHigh affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Polypeptides: High affinity immunoglobulin gamma Fc receptor ILeukocyte immunoglobulin-like receptor subfamily B member 2
go.drugbank.com/bio_entities/BE0010561TargetHumansRecognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells … Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles (PubMed:11169396, PubMed:12853576, PubMed:16455647, PubMed:20448110, PubMed:27859042).
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily B member 2Synonyms: Immunoglobulin-like transcript 4, Leukocyte immunoglobulin-like receptor 2High affinity immunoglobulin epsilon receptor subunit alpha
go.drugbank.com/bio_entities/BE0000015TargetHumansHigh-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells.
Polypeptides: High affinity immunoglobulin epsilon receptor subunit alphaLeukocyte immunoglobulin-like receptor subfamily A member 4
go.drugbank.com/bio_entities/BE0013620TargetHumansFunctions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic ...
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily A member 4Synonyms: Immunoglobulin-like transcript 7, CD85 antigen-like family member GLeukocyte immunoglobulin-like receptor subfamily B member 4
go.drugbank.com/bio_entities/BE0017129TargetHumansInhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance (PubMed:11875462). Receptor for FN1 (PubMed:34089617). Receptor for apolipoprotein APOE (PubMed:30333625). Receptor for AL...
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily B member 4Synonyms: Immunoglobulin-like transcript 3, Leukocyte immunoglobulin-like receptor 5