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Displaying results 31 - 40 of 2572 in total
  1. Pathway

    Glycine and Serine Metabolism

    smpdb.ca/view/SMP0000004
    Metabolic

    This pathway describes the synthesis and breakdown of several small amino acids, including glycine, serine, and cysteine. All of these compounds share common intermediates and almost all can be biosynthesized from one another. Serine and...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  2. Pathway

    Dihydropyrimidine Dehydrogenase Deficiency (DHPD)

    smpdb.ca/view/SMP0000179
    Disease

    Dihydropyrimidine Dehydrogenase Deficiency (DHPD; Thymine-uraciluria) is a rare autosomal recessive disorder caused by a mutation in the DPYD gene which codes for dihydropyrimidine dehydrogenase. A deficiency in this enzyme results in ac...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  3. Pathway

    Dimethylglycine Dehydrogenase Deficiency

    smpdb.ca/view/SMP0000242
    Disease

    Dimethylglycine dehydrogenase deficiency, also called DMGDH deficiency and dimethylglycinuria, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of glycine metabolism caused by a defective DMGDH gene. DMGDH code...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  4. Pathway

    Hyperglycinemia, Non-Ketotic

    smpdb.ca/view/SMP0000485
    Disease

    Nonketotic hyperglycinemia (GCE) is a rare inborn error of metabolism (IEM) and autosomal recessive disorder caused by a defective GLDC gene. GLDC encodes for the enzymes involved in the conversion of glycine to CO2, NH3 and hydroxymethy...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  5. Pathway

    3-Phosphoglycerate Dehydrogenase Deficiency

    smpdb.ca/view/SMP0125581
    Disease

    3-Phosphoglycerate dehydrogenase deficiency is a disorder of L-serine biosynthesis that is characterized by congenital microcephaly, psychomotor retardation, and seizures.The disorder is caused by homozygous or compound heterozygous or h...

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 more
  6. Pathway

    Phosphatidylcholine Biosynthesis PC(14:0/14:0)

    smpdb.ca/view/SMP0014216
    Metabolic

    PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  7. Pathway

    Phosphatidylcholine Biosynthesis PC(14:0/14:1(9Z))

    smpdb.ca/view/SMP0014217
    Metabolic

    PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  8. Pathway

    Phosphatidylcholine Biosynthesis PC(14:0/15:0)

    smpdb.ca/view/SMP0014218
    Metabolic

    PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  9. Pathway

    Phosphatidylcholine Biosynthesis PC(14:0/16:0)

    smpdb.ca/view/SMP0014219
    Metabolic

    PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
  10. Pathway

    Phosphatidylcholine Biosynthesis PC(14:0/16:1(9Z))

    smpdb.ca/view/SMP0014220
    Metabolic

    PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more