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Displaying results 31 - 40 of 2506 in total
  1. Drug

    Dorzolamide

    go.drugbank.com/drugs/DB00869
    ApprovedInvestigational

    [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]

    Mixtures: Cosopt PF, Cosopt PFCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  2. Drug

    Nitroprusside

    go.drugbank.com/drugs/DB00325
    ApprovedInvestigational

    Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing...

    Products: H0-P3
  3. Drug

    Rivaroxaban

    go.drugbank.com/drugs/DB06228
    ApprovedInvestigational

    Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Ixobran 15 (Rivaroxaban Tablet Ph Eur 15mg), Ixobran 10 (Rivaroxaban Tablet Ph Eur 10mg)
  4. Drug

    Naphazoline

    go.drugbank.com/drugs/DB06711
    Approved

    Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles . It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations . Naphazoline was firs...

    Products: Pi Yen Chin, Pi Yuan Chin
  5. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 b...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: REQUIP PD 24 HOUR, REQUIP PD 24 HOUR 2mg Prolonged Release Tablets
  6. Drug

    Propylene glycol

    go.drugbank.com/drugs/DB01839
    ApprovedInvestigational

    A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.

    Mixtures: Hydration PF, Systane Hydration PF Preservative FreeProducts: Systane COMPLETE PF
  7. Drug

    Neomycin

    go.drugbank.com/drugs/DB00994
    ApprovedInvestigationalVet approved

    Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framyce...

    Mixtures: KRIM PI KANG SHUANG, PS-2261 Triple Antibiotic, 0.5gProducts: NEOMYCIN PF-50% W/W POWDER
  8. Drug

    Butylene glycol

    go.drugbank.com/drugs/DB14110
    Approved

    Products: PLAY and JOY Cologne Maca Extra Hot Lubricant PJ-LBS201-35EU
  9. Drug

    Fluvastatin

    go.drugbank.com/drugs/DB01095
    ApprovedInvestigational

    Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynth...

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP1A1 SubstratesProducts: FLUVASTATIN 1A PH 80MG RET
  10. Drug

    Clopidogrel

    go.drugbank.com/drugs/DB00758
    ApprovedInvestigational

    ,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent

    Categories: Cytochrome P-450 CYP1A2 Substrates, Cytochrome P-450 CYP2B6 InhibitorsProducts: CLOPID, CLOTIX