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Ambroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalIt stimulates synthesis and release of surfactant by type II pneumocytes. … Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin.
Synonyms: Cyclohexanol, 4-((2-amino-3,5-dibromobenzyl)amino)- (E)-, N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanolMixtures: AMBROXOL 150 MG / 100 ML + CLENBUTEROL 0.1 MG / 100 ML SOLUCIÓN ORAL NIÑOS, AMBROXOL 300 MG/100 ML + CLENBUTEROL 0.2 MG/100 MLSOLUCIÓN ORAL ADULTOSGliclazide
go.drugbank.com/drugs/DB01120ApprovedInvestigationalGliclazide is extensively metabolized by the liver; its metabolites are excreted in both urine (60-70%) and feces (10-20%). … a sulfonamide group able to release a proton and the presence of one aromatic group.
Mixtures: DUODİA 80 MG/500 MG TABLET, 30 ADET, DUODIA 80/500 MG TABLET, 60 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesFlupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnIt exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. … Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid.
Mixtures: DORMIR TABLET, 20 ADETCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-RingCenobamate
go.drugbank.com/drugs/DB06119ApprovedInvestigationalCenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures. … [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABA<sub>A</sub> and inhibits voltage gated sodium channels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: XCOPRI TITRATION PACK 50 mg, 100 mg, XCOPRI TITRATION PACK 12.5 mg, 25 mgMenadione
go.drugbank.com/drugs/DB00170ApprovedNutraceuticalA synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Synonyms: Vitamin K 3, 2-Methyl-1,4-naphthochinonMixtures: LIBAVIT-K 20 MG AMPUL, 5 ADETAmphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalconcentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. … Amphotericin B shows a high order of in vitro activity against many species of fungi.
Synonyms: AMPH-b, Amfotericina BSalts: Amphotericin B Cholesteryl Sulfate ComplexRanolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigational[L3580] With a mechanism of action different from drugs used to treat the same condition, ranolazine is a promising anti-anginal therapy. It was originally approved by the FDA in 2006.[L5440] … Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: RANEXICOR ® 500, RANOLAZINA EGAtracurium
go.drugbank.com/drugs/DB13295ApprovedInvestigationalWithdrawnCategories: Heterocyclic Compounds, 2-RingProducts: TRACRİUM 50 MG/5 ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 5 ADET, NEUCURIUM 50 MG/5 ML IV INFUZYON VE ENJEKSIYON ICIN COZELTI ICEREN AMPUL, 5 ADETCiticoline
go.drugbank.com/drugs/DB12153ApprovedInvestigationalWithdrawnCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Cytidine 5'-diphosphocholine, Cytidine-5'-diphosphocholineFerric cation
go.drugbank.com/drugs/DB13949ApprovedWithdrawnIron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. … Ferric citrate (tetraferric tricitrate decahydrate) is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.
Mixtures: MALTOFER FOL 100 MG/0.35 MG TABLET, 30 ADETSynonyms: iron(3+)