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Displaying results 391 - 400 of 10000 in total
  1. Drug

    Mefenamic acid

    go.drugbank.com/drugs/DB00784
    Approved

    It is an inhibitor of cyclooxygenase.

    Synonyms: N-2,3-xylylanthranilic acid, N-(2,3-xylyl)-2-aminobenzoic acidMixtures: ORCIGESIC TABLETS
  2. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    effects are thought to be produced by 8-chlorotheophylline's adenosine receptor blockade. … [L32985] The antiemetic properties of dimenhydrinate are primarily thought to be produced by diphenhydramine's antagonism of H1 histamine receptors in the vestibular system[A1540] while the excitatory

    Synonyms: N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate, 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)Products: XAMAMINA MAL DI VIAGGIO, ANTI-EM 50 MG TABLET, 12 ADET
  3. Drug

    Apixaban

    go.drugbank.com/drugs/DB06605
    ApprovedInvestigational

    Apixaban was approved by the FDA on December 28, 2012[L6043]. … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic

    Products: APIXABAN EG, KEIXA 5MG TABLETAS RECUBIERTAS
  4. Drug

    Ticagrelor

    go.drugbank.com/drugs/DB08816
    ApprovedInvestigational

    [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207]. Ticagrelor was granted EMA approval on 3 December 2010. … Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism.

    Synonyms: (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diolProducts: TICAGRELOR DR. REDDY'S, TIARE® TABLETAS 90 MG
  5. Drug

    Diltiazem

    go.drugbank.com/drugs/DB00343
    ApprovedInvestigational

    [L10556] Compared to dihydropyridine drugs, such as [nifedipine], that preferentially act on vascular smooth muscle and [verapamil] that directly acts on the heart muscle, diltiazem displays an intermediate … , and rest-related cramps in the lower extremities.

    Synonyms: d-cis-diltiazemProducts: TILAZEM RETARD TABLETAS DE 180MG, Penta-diltiazem - 30mg
  6. Drug

    Valsartan

    go.drugbank.com/drugs/DB00177
    ApprovedInvestigational

    [A174124,A178153,A173869,A185324,A185327,A185333,A185342,A185345] Valsartan also slows the progression of diabetic nephropathy due to its renoprotective effects. … [A174124,A173869] Valsartan was initially approved in 1996 in Europe for the treatment of hypertension in adults. Shortly after, in 1997, this drug was approved in the United States.

    Mixtures: RACORVAL D 80/12.5 MG TABLETAS RECUBIERTAS., RACORVAL D 80/12.5 MG TABLETAS RECUBIERTAS.Categories: Agents Acting on the Renin-Angiotensin System
  7. Indication

    Torsades de Pointes

    go.drugbank.com/conditions/DBCOND0000480
    Drugs: Isoprenaline · Magnesium sulfate
    Synonyms: Torsades de Pointes, Torsade de Pointes
  8. Drug

    Quetiapine

    go.drugbank.com/drugs/DB01224
    ApprovedInvestigational

    It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189] … Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder.

    Categories: Dopamine D2 Receptor AntagonistsProducts: KETIAN 25MG CAPSULA BLANDA DE GELATINA, DRUGTECH QUETIDIN XR COMPRIMIDOS RECUBIERTOS DE LIBERACION PROLONGADA 400 MG
  9. Drug

    Ofloxacin

    go.drugbank.com/drugs/DB01165
    ApprovedInvestigational

    A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

    Products: FLOXSTAT (R)TABLETAS DE 200 MG, OFLOMIXIN TABLETAS
  10. Drug

    Tapentadol

    go.drugbank.com/drugs/DB06204
    ApprovedInvestigational

    [A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited alternative treatment options.

    Products: Nucynta ER Tablets 50 mg, Nucynta ER Tablets 100 mg