Search

Displaying results 391 - 400 of 10000 in total
  1. Drug

    Tapentadol

    go.drugbank.com/drugs/DB06204
    ApprovedInvestigational

    [A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: PALEXIS® RETARD 25MG, NUCYNTA ER Tablets 250mg
  2. Drug

    Levothyroxine

    go.drugbank.com/drugs/DB00451
    ApprovedInvestigational

    [F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system. … [F4636,A35722] In response to Thyroid Stimulating Hormone (TSH) release by the pituitary gland, a normally functioning thyroid gland will produce and secrete T<sub>4</sub>, which is then converted through

    Mixtures: Levothyroxine and Liothyronine Thyroid, Levothyroxine and Liothyronine ThyroidCategories: Sex Hormones and Insulins, Amino Acids, Peptides, and Proteins
  3. Drug

    Ertugliflozin

    go.drugbank.com/drugs/DB11827
    ApprovedInvestigational

    [A31581] Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.[L48621] … Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus.

    Mixtures: Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated Tablets, Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated TabletsCategories: Alimentary Tract and Metabolism, metformin and ertugliflozin
  4. Drug

    Hydroquinone

    go.drugbank.com/drugs/DB09526
    ApprovedInvestigational

    It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen. … , sunspots, and freckles.

    Mixtures: Throwers Pbc No. 1, Condition and Enhance System Full-size Non-surgicalProducts: SLMD Skincare by Sandra Lee, M.D. - Dark Spot Fix, NU-DERM CLEAR Skin Bleaching and Corrector
  5. Drug

    Empagliflozin

    go.drugbank.com/drugs/DB09038
    ApprovedInvestigational

    [L13688] The first known inhibitor of SGLTs, phlorizin, was isolated from the bark of apple trees in 1835 and researched extensively into the 20th century, but was ultimately deemed inappropriate for … [remogliflozin etabonate]), but these molecules proved relatively pharmacokinetically unstable.

    Mixtures: Glyxambi Film-Coated Tablets 10mg/5mg, Glyxambi Film-Coated Tablets 25mg/5mgCategories: Alimentary Tract and Metabolism, metformin and empagliflozin
  6. Drug

    Trazodone

    go.drugbank.com/drugs/DB00656
    ApprovedInvestigational

    [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine … [T646] A unique feature of this drug is that it does not promote the anxiety symptoms, sexual symptoms, or insomnia, which are commonly associated with SSRI and SNRI therapy.

    Categories: Serotonin antagonist and reuptake inhibitors (SARIs), Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Nu-trazodone - Tab 100mg, Nu-trazodone-D - Tab 150mg
  7. Drug

    Triclosan

    go.drugbank.com/drugs/DB08604
    Approved

    An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. … , sports equipment and shoes.

    Mixtures: Benzocaine and Triclosan, Benzocaine and TriclosanCategories: Phenol and Derivatives, Antiseptics and Disinfectants
  8. Pathway

    Glutaminolysis and Cancer

    smpdb.ca/view/SMP0002298
    Disease

    Glutamine not only provides a major substrate for respiration but also for the synthesis of other macromolecules, such as nucleotides, proteins and hexosamines. … The transportation of glutamine in and out regulates mTOR activation to coordinate cell growth and proliferation.

    Drugs: Pyridoxal phosphate · Pyruvic acid · Biotin · Aspartic acid · L-Glutamine · Succinic acid +9 more
  9. Drug

    Hydrocodone

    go.drugbank.com/drugs/DB00956
    ApprovedIllicitInvestigational

    Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by [dextromethorphan] in current cough and cold formulations. … Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is frequently used in cases of severe pain.

    Mixtures: FEMTAX® 5MG/325MG, Co-gesicCategories: Cough and Cold Preparations, hydrocodone and ibuprofen
  10. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. … [A7514] The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity.

    Mixtures: TRIUMEQ FILM COATED TABLET 50mg/600mg/300mgCategories: lamivudine and dolutegravir, dolutegravir and rilpivirine