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Iron Dextran
go.drugbank.com/drugs/DB00893ApprovedInvestigationalVet approvedIron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. … Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.
Mixtures: Se-Tan DHA, Se-Tan DHAProducts: Cosmofer 50mg/ml Solution for injection and for infusion, FERRO 2000 SOLUTION FOR INJECTIONVigabatrin
go.drugbank.com/drugs/DB01080ApprovedInvestigationalVigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. … [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its US approval by the FDA in 2009 mandated the creation of a drug registry to monitor patients for visual
Categories: Cytochrome P-450 CYP2C9 Inducers, Cytochrome P-450 Enzyme InducersProducts: Vigabatrin for Oral Solution, Vigabatrin for oral solution USP, 500 mgPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. … It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of _Pseudomonas aeruginosa_[FDA Label].
Mixtures: Premier Value Max Strength Antibiotic plus pain relief, OTEK-P EAR DROPSCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseInsulin degludec
go.drugbank.com/drugs/DB09564ApprovedInvestigationalInsulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. … [A18561,A18562,A18563,A18564,A174934] Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis and proteolysis among many other functions.
Mixtures: Ryzodeg® FlexTouch® 100 U/ml Solution for InjectionCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersDupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigational[A180478] As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in … [L7186] Dupilumab is commonly marketed as Dupixent, which is available as a formulation for subcutaneous injection. It was first approved by the FDA in 2017.
Categories: Agents for Dermatitis, Excluding Corticosteroids, Interleukin-4 Receptor alpha AntagonistProducts: Dupixent 300 mg Solution for Injection in Pre-filled Syringe, Dupixent 200mg Solution for Injection in Pre-Filled SyringeInsulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalInsulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis and proteolysis among many other functions. … Absorption of glucose into cells allows for its transformation into glycogen or fat for storage.
Mixtures: Ryzodeg® FlexTouch® 100 U/ml Solution for InjectionCategories: Insulins and Analogues for Injection, Fast-Acting, Cytochrome P-450 CYP1A2 InducersSelenium
go.drugbank.com/drugs/DB11135ApprovedInvestigationalVet approvedSelenium is a trace metal in the human body particularly important as a component of glutathione peroxidase, an important enzyme in the prevention of cellular damage by free radicals and reactive oxygen
Mixtures: For Men, PM CapsProducts: selenase 500 micrograms, solution for injection (50 micrograms/ml), selenase ® 100 micrograms, solution for injection (50 micrograms/ml)Ixekizumab
go.drugbank.com/drugs/DB11569ApprovedInvestigationalIxekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. … It is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
Products: Taltz 80mg solution for injection in pre-filled pen, TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/mlCetrorelix
go.drugbank.com/drugs/DB00050ApprovedInvestigationalCetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). … When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not ready for fertilization to be released.
Categories: Gonadotropin Releasing Hormone Receptor AntagonistsProducts: Cetrotide 0.25 mg powder and solvent for solution for injection, Asporelix 0.25 (Cetrorelix 0.25mg Powder and Solvent for Solution for Injection)Eszopiclone
go.drugbank.com/drugs/DB00402ApprovedInvestigationalThis sets it apart from many other hypnotic sedatives, which are generally approved only for the relief of short-term (6-8 weeks) insomnia. Eszopiclone was initially approved by the FDA in 2004. … One major benefit of eszopiclone is that it is approved by the FDA for the long-term treatment of insomnia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Mar-eszopiclone