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Omeprazole
go.drugbank.com/drugs/DB00338ApprovedInvestigationalVet approvedOriginally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases cha...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: OMEPRAZOLO P-CARE, Omeprazol G.L. 40 mg - KapselnIophendylate
go.drugbank.com/drugs/DB01187ApprovedIophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially...
Synonyms: Ethyl 10-(p-iodophenyl)-undecanoate, Ethyl 10-(p-iodophenyl)undecylateAmifampridine
go.drugbank.com/drugs/DB11640ApprovedPatients with LEMS develop serum antibodies against presynaptic P/Q-type voltage-gated calcium channels, leading to decreased presynaptic calcium levels and reduced quantal release of acetylcholine, which
Vincristine
go.drugbank.com/drugs/DB00541ApprovedInvestigationalIt is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsVestronidase alfa
go.drugbank.com/drugs/DB12366ApprovedInvestigationalThe enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as human beta-glucuronidase (GUS) [FDA Label].
Deoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalIt is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical
Relatlimab
go.drugbank.com/drugs/DB14851ApprovedInvestigational[L41305] As immune checkpoint inhibitors have limited efficacy when used alone, drugs like relatlimab have been trialed in combination with other checkpoint inhibitors - for example, PD-1 inhibitors like … [A246155] Relatlimab received FDA approval in March 2022, alongside the PD-1 inhibitor [nivolumab] in the combination product Opdualag (Bristol-Myers Squibb), for the treatment of unresectable or metastatic
Momordica charantia fruit
go.drugbank.com/drugs/DB14265InvestigationalMomordica charantia fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Ku GuaAvelumab
go.drugbank.com/drugs/DB11945ApprovedInvestigationalAvelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors