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Displaying results 3991 - 4000 of 10000 in total
  1. Drug

    Propanidid

    go.drugbank.com/drugs/DB13234
    Experimental

    An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)

  2. Drug

    MK-0767

    go.drugbank.com/drugs/DB12055
    Investigational

    MK0767 has been used in trials studying the treatment of Dyslipidemia, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Diabetes Mellitus, Type II, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Binetrakin

    go.drugbank.com/drugs/DB12182
    Investigational

    Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among

    Categories: Interleukin-4, antagonists & inhibitorsSynonyms: IL-4, Interleukin-4
  4. Drug

    Eleclazine

    go.drugbank.com/drugs/DB12394
    Investigational

    Eleclazine has been used in trials studying the treatment of LQT2 Syndrome, Long QT Syndrome, Ischemic Heart Disease, Ventricular Arrhythmia, and Long QT Syndrome Type 3, among others.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-(pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one
  5. Drug

    Evogliptin

    go.drugbank.com/drugs/DB12625
    Investigational

    Evogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2.

    Categories: Dipeptidyl Peptidase 4, Heterocyclic Compounds, 1-Ring
  6. Drug

    AVR-RD-04

    go.drugbank.com/drugs/DB18644
    Experimental

    AVR-RD-04 is an investigational gene therapy for cystinosis. … It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.

    Synonyms: autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin
  7. Drug

    Cry5B

    go.drugbank.com/drugs/DB17783
    Experimental

    Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis_. … With demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal infections.[A259372, A259377]

  8. Drug

    Bicuculline

    go.drugbank.com/drugs/DB11562
    Experimental

    Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. … It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.

    Categories: GABA-A Receptor Antagonists, Heterocyclic Compounds, 2-RingSynonyms: d-Bicuculline
  9. Drug

    Ultevursen

    go.drugbank.com/drugs/DB17835
    Investigational

    Ultevursen is a single-stranded RNA-based oligonucleotide targeting exon 13 of the USH2A gene that encodes usherin.

  10. Target

    Tyrosine-protein kinase ABL2

    go.drugbank.com/bio_entities/BE0000435
    TargetHumans

    and adhesion and receptor endocytosis. … Phosphorylates multiple receptor tyrosine kinases like PDGFRB and other substrates which are involved in endocytosis regulation such as RIN1.

    Synonyms: Abelson-related gene protein