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Tecadenoson
go.drugbank.com/drugs/DB04954InvestigationalIt is being developed by CV Therapeutics, Inc. … Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for the conversion of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm.
Latrunculin B
go.drugbank.com/drugs/DB08080ExperimentalLatrunculin B is a 14-membered macrolide attached to 2-thiazolidinone moiety, isolated from Red Sea sponge _Latrunculia magnifica_.
Povidone K30
go.drugbank.com/drugs/DB14478ApprovedA polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander. See povidone for full details.
Dimethyl sulfoxide
go.drugbank.com/drugs/DB01093ApprovedInvestigationalVet approvedBecause of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation.
Synonyms: S(O)Me2Estramustine
go.drugbank.com/drugs/DB01196ApprovedWithdrawnA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Synonyms: Estradiol 3-(N,N-bis(2-chloroethyl)carbamate)Caprospinol
go.drugbank.com/drugs/DB05263ExperimentalCaprospinol (SP-233) is the first drug ever to demonstrate the correlation of clearing beta-amyloid from the brain. It also improves the brain histopathology and recovers memory function.
Doxofylline
go.drugbank.com/drugs/DB09273InvestigationalAs a drug used in the treatment of asthma, doxofylline has shown similar efficacy to theophylline but with significantly fewer side effects in animal and human studies. … Decreased affinity for adenosine receptors may account for the better safety profile of doxofylline compared to theophylline [L1169].
Stem-cell derived exosome vesicle products
go.drugbank.com/drugs/DB15743ExperimentalOnce secreted into extracellular fluid, exosomes are taken up by their target cells or carried to distant target sites. … Exosomes from MSCs carry cytokines and growth factors, like TGFB1, IL-6, IL-10, and hepatocyte growth factor (HGF); all are shown to be immunomodulatory.
Flubendazole
go.drugbank.com/drugs/DB08974ApprovedInvestigationalWithdrawnFlubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
Dengue virus serotype 4
go.drugbank.com/drugs/DB22667ApprovedDengue virus serotype 4 is a serotype of _Orthoflavivirus denguei_ known to cause dengue fever. … [A274008] It is one of four serotypes covered by Qdenga, a live, attenuated, tetravalent vaccine used for the prevention of dengue disease.