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MK-1496
go.drugbank.com/drugs/DB12763InvestigationalMK-1496 has been used in trials studying the treatment of Neoplasms and Malignant.
Stearic acid
go.drugbank.com/drugs/DB03193ApprovedStearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Products: K Oxiderm Op, K Oxiderm OP Post Procedure skin care bruiseDinutuximab
go.drugbank.com/drugs/DB09077ApprovedInvestigationalBy binding to GD2, dinutiximab induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity of tumor cells thereby leading to apoptosis and inhibiting proliferation of the … It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions of human IgG1 heavy-chain and kappa light-chain.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsAmsacrine
go.drugbank.com/drugs/DB00276ApprovedInvestigationalWithdrawnIt produces consistent but acceptable myelosuppression and cardiotoxic effects. … It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors.
Categories: Indicators and Reagents, Antineoplastic and Immunomodulating AgentsProducts: Amsidyl 75 mg/1,5 ml Konzentrat und Lösungsmittel für ein Konzentrat zur Herstellung einer InfusionslösungMK-0736
go.drugbank.com/drugs/DB15209InvestigationalMK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial Plaque (0736-006)(TERMINATED)).
Calcitonin gene-related peptide
go.drugbank.com/drugs/DB06379InvestigationalA 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. … The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
Categories: Amino Acids, Peptides, and ProteinsLumasiran
go.drugbank.com/drugs/DB15935ApprovedInvestigational[L23554] This condition, caused by a deficiency in the enzyme alanine-glyoxylate aminotransferase, leads to an accumulation of oxalate, causing calcium crystal formation. … [L23554] These patients experience frequent kidney stones, nephrocalcinosis, and renal failure.
Categories: Alimentary Tract and Metabolism, Nucleic Acids, Nucleotides, and NucleosidesModafinil
go.drugbank.com/drugs/DB00745ApprovedInvestigationalNarcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. … The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular
Categories: Modafinil and isomer, Metabolic Side Effects of Drugs and SubstancesDigoxin Immune Fab (Ovine)
go.drugbank.com/drugs/DB00076ApprovedDigoxin Immune Fab is a sheep antibody (26-10) FAB fragment from sheep immunized with the digoxin derivative Digoxindicarboxymethylamine. It is used as an antidote for overdose of digoxin.
Categories: Amino Acids, Peptides, and ProteinsAnisotropine methylbromide
go.drugbank.com/drugs/DB00517ApprovedIts use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. … Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant