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Displaying results 4001 - 4010 of 10000 in total
  1. Drug

    Velaglucerase alfa

    go.drugbank.com/drugs/DB06720
    Approved

    Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. … Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.

    Products: VPRIV 400 ÜNİTE İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 25 ADET, VPRIV 400 ÜNİTE İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET
  2. Drug

    Nuvaxovid

    go.drugbank.com/drugs/DB15810
    ApprovedInvestigational

    [A243789, A243794, A243799] The European Commission granted Novavax conditional marketing authorization for nuvaxovid for active immunization to prevent COVID-19 caused by SARS-CoV-2 on December 20, … Nuvaxovid (NVX-CoV2373) contains a recombinant mutant S protein that is codon-optimized for baculovirus-mediated expression in Sf9 cells derived from _Spodoptera frugiperda_ together with a Matrix-M adjuvant

    Categories: COVID-19 VaccinesSynonyms: SARS-CoV-2 rS, SARS-CoV-2 rS Nanoparticle Vaccine
  3. Drug

    Cobalamin

    go.drugbank.com/drugs/DB14098
    ApprovedInvestigational

    Mixtures: Folika-MG, Multi 12Categories: Vitamin B 12, biosynthesis, Heterocyclic Compounds, 1-Ring
  4. Drug

    Interferon alfa-2a

    go.drugbank.com/drugs/DB00034
    ApprovedInvestigationalWithdrawn

    Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. … It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.

    Synonyms: Interferon Alfa 2A, Interferon alfa-2aInternational brands: Roferon A
  5. Target

    5-aminolevulinate synthase, non-specific, mitochondrial

    go.drugbank.com/bio_entities/BE0000409
    TargetHumans

    Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products

    Polypeptides: 5-aminolevulinate synthase, non-specific, mitochondrialSynonyms: 5-aminolevulinic acid synthase 1
  6. Target

    C-C chemokine receptor type 5

    go.drugbank.com/bio_entities/BE0000911
    TargetHumans

    Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granuloc...

    Polypeptides: C-C chemokine receptor type 5Synonyms: CCR-5, CC-CKR-5
  7. Target

    5-phosphohydroxy-L-lysine phospho-lyase

    go.drugbank.com/bio_entities/BE0002164
    TargetHumans

    Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde

    Polypeptides: 5-phosphohydroxy-L-lysine phospho-lyase
  8. Target

    Neuronal acetylcholine receptor subunit alpha-5

    go.drugbank.com/bio_entities/BE0003586
    TargetHumans

    Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collecti...

    Polypeptides: Neuronal acetylcholine receptor subunit alpha-5
  9. Target

    Cyclin-dependent kinase 5 activator 1

    go.drugbank.com/bio_entities/BE0003819
    TargetHumans

    p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex...

    Polypeptides: Cyclin-dependent kinase 5 activator 1Synonyms: Cyclin-dependent kinase 5 regulatory subunit 1
  10. Target

    Cytochrome b6-f complex subunit 5

    go.drugbank.com/bio_entities/BE0003906
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assemb...

    Polypeptides: Cytochrome b6-f complex subunit 5