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Famprofazone
go.drugbank.com/drugs/DB16702ExperimentalFamprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan.
Tallimustine
go.drugbank.com/drugs/DB15466Experimental[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as [brostallicin], which have a favourable cytotoxicity
Brilaroxazine
go.drugbank.com/drugs/DB09226InvestigationalAs of May 2015, it is in phase III clinical trials for schizophrenia.
Aceprometazine
go.drugbank.com/drugs/DB01615ExperimentalAceprometazine is a is a drug with neuroleptic and anti-histamine properties. Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.
Cabotegravir
go.drugbank.com/drugs/DB11751ApprovedInvestigationalCabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine. Early research into cabotegravir showed it had lower oral bioavailability than dolutegr...
Ethyl pyruvate
go.drugbank.com/drugs/DB05869InvestigationalCTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancr...
Abivertinib
go.drugbank.com/drugs/DB15327Investigationalcytokines at once, it may provide more pronounced clinical benefits as compared to agents targeting single pathways (e.g. interleukin-6 inhibitors). … [L17388,L17393] The cytokine storm associated with COVID-19 is thought to contribute to disease progression and is associated with poor outcomes in patients - as abivertinib inhibits the release of multiple
Mevastatin
go.drugbank.com/drugs/DB06693ExperimentalIt has served as one of the lead compounds for the development of the synthetic compounds used today. … It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins.
UB-612
go.drugbank.com/drugs/DB16444InvestigationalThe UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components[L30653]. … The vaccine incorporates a strong S1-RBD component linked to a single chain fragment region (sFC) of a human IgG1, which facilitates cell attachment and acts as the principal neutralizing domain of the
NTx-265
go.drugbank.com/drugs/DB05649InvestigationalIt is also investigating use of the compound for neurodegenerative disorders, such as Huntington’s disease and Alzheimer’s disease.