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Bicifadine
go.drugbank.com/drugs/DB04889InvestigationalBicifadine was shown to have potent analgesic activity in vivo and was chosen for further development for the treatment of pain. … It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a non-narcotic profile.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesHalothane
go.drugbank.com/drugs/DB01159ApprovedVet approvedWithdrawnAnalgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required.
Categories: NMDA Receptor Antagonists, Cytochrome P-450 SubstratesCytarabine
go.drugbank.com/drugs/DB00987ApprovedInvestigationalCytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Alexan 100 mg/ml - Konzentrat zur Herstellung einer InfusionslösungClomifene
go.drugbank.com/drugs/DB00882ApprovedInvestigationalA triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Synonyms: 2-(p-(β-chloro-α-phenylstyryl)phenoxy)triethylamine, 2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)triethylamineCategories: P-glycoprotein substrates, Estrogen Receptor ModulatorsAceclidine
go.drugbank.com/drugs/DB13262ApprovedAceclidine is a cholinergic muscarinic agonist which began marketing in Europe in the 1970s for the treatment of glaucoma. … [A274278] Aceclidine was approved the US FDA in July 2025 for the treatment of adult patients with presbyopia.[L53768]
Categories: Cholinergic Receptor AgonistRelutrigine
go.drugbank.com/drugs/DB21614InvestigationalRelutrigine is under investigation in clinical trial NCT07010471 (A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine).
Dexchlorpheniramine
go.drugbank.com/drugs/DB13679InvestigationalIt is an antihistamine drug with anticholinergic (drying) and sedative actions. It disrupts histamine signaling by competing with histamine for cell receptor sites on effector cells. … The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions.
Categories: Antihistamines for Systemic Use, Cytochrome P-450 SubstratesNitisinone
go.drugbank.com/drugs/DB00348ApprovedNitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1 and Alkaptonuria. It is sold under the brand names Orfadin and Harliku.
Synonyms: 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedioneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLauric acid
go.drugbank.com/drugs/DB03017ApprovedLauric acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression. … Lauric acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.