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Displaying results 4021 - 4030 of 10000 in total
  1. Target

    Pyridoxal 5'-phosphate synthase subunit Pdx1

    go.drugbank.com/bio_entities/BE0009271
    TargetPlasmodium falciparum (isolate 3D7)

    Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by Pdx2. … Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.

    Polypeptides: Pyridoxal 5'-phosphate synthase subunit Pdx1
  2. Target

    G protein-coupled receptor kinase 5

    go.drugbank.com/bio_entities/BE0013072
    TargetHumans

    Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G protein-coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization,...

    Polypeptides: G protein-coupled receptor kinase 5
  3. Target

    Short transient receptor potential channel 5

    go.drugbank.com/bio_entities/BE0021113
    TargetHumans

    Forms a receptor-activated non-selective calcium permeant cation channel (PubMed:16284075, PubMed:38959890, PubMed:37137991). Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with...

    Polypeptides: Short transient receptor potential channel 5Synonyms: hTRP-5, TRP-5
  4. Drug

    Meldonium

    go.drugbank.com/drugs/DB13723
    Investigational

    Products: SATURID 100 MG/ ML I.V. ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL
  5. Pathway

    Cardiolipin Biosynthesis CL(10:0/20:0/20:0/i-20:0)

    smpdb.ca/view/SMP0178977
    Metabolic

    Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  6. Drug

    Hydroquinone

    go.drugbank.com/drugs/DB09526
    ApprovedInvestigational

    As a result of these concerns, hydroquinone has been banned in the EU and UK. … It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen.

    Mixtures: I-max Lightening 5, Porcelana 24 Hour Skin LighteningCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Liotrix

    go.drugbank.com/drugs/DB01583
    Approved

    It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. … It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues.

    Categories: l-Triiodothyronine, P-glycoprotein inducersProducts: LEVOTIROXINA 150 MCG TABLETA
  8. Drug

    Festuca pratensis pollen

    go.drugbank.com/drugs/DB10370
    Approved

    Festuca pratensis pollen is the pollen of the Festuca pratensis plant. Festuca pratensis pollen is mainly used in allergenic testing.

    Mixtures: 6 Grass Mix, 6 Grass MixProducts: Standardized Grass Pollen - Meadow Fescue (100 Bau/ml), Standardized Grass Pollen - Meadow Fescue (1000 Bau/ml)
  9. Drug

    Aclidinium

    go.drugbank.com/drugs/DB08897
    Approved

    It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.

    Mixtures: Duaklir Genuair 340/12 mcg Inhalation Powder, DUAKLIR®GENUAIR®340/12MCG/DOSIS.Products: EKLIRA®GENUAIR® 322 MCG/DOSIS, Eklira Genuair 322 mcg Inhalation Powder
  10. Drug

    Nuvaxovid

    go.drugbank.com/drugs/DB15810
    ApprovedInvestigational

    [A243789, A243794, A243799] The European Commission granted Novavax conditional marketing authorization for nuvaxovid for active immunization to prevent COVID-19 caused by SARS-CoV-2 on December 20, … Nuvaxovid (NVX-CoV2373) contains a recombinant mutant S protein that is codon-optimized for baculovirus-mediated expression in Sf9 cells derived from _Spodoptera frugiperda_ together with a Matrix-M adjuvant

    Categories: COVID-19 VaccinesSynonyms: SARS-CoV-2 rS, SARS-CoV-2 rS Nanoparticle Vaccine