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Displaying results 4041 - 4050 of 10000 in total
  1. Drug

    Pyrazoloacridine

    go.drugbank.com/drugs/DB12549
    Investigational

    Pyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Sodium sulfate

    go.drugbank.com/drugs/DB09472
    ApprovedInvestigationalVet approved

    Sodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. … Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions.

  3. Drug

    MLN576

    go.drugbank.com/drugs/DB06517
    Experimental

    XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.[A234609]

    Categories: Topoisomerase I Inhibitors, Topoisomerase II Inhibitors
  4. Drug

    Tazarotene

    go.drugbank.com/drugs/DB00799
    Approved

    It is a prodrug that is found in topical formulations used in the treatment of various conditons, such as psoriasis, acne, and sun damaged skin (photodamage). … Tazarotene, commonly marketed as Tazorac®, Avage®, and Zorac®, is member of the acetylenic class of retinoids.

  5. Drug

    AT9283

    go.drugbank.com/drugs/DB05169
    Investigational

    AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. … It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.

  6. Drug

    Denopamine

    go.drugbank.com/drugs/DB21277
    Experimental

    Denopamine is a small molecule drug. Denopamine has a monoisotopic molecular weight of 317.16 Da.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Sufugolix

    go.drugbank.com/drugs/DB06494
    Experimental

  8. Drug

    Z-Val-Ala-Asp fluoromethyl ketone

    go.drugbank.com/drugs/DB07744
    Experimental

    It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.

    Synonyms: N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamideCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Egtazic acid

    go.drugbank.com/drugs/DB19986
    Experimental

    Egtazic acid is a small molecule drug. Egtazic acid has a monoisotopic molecular weight of 380.14 Da.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Evofosfamide

    go.drugbank.com/drugs/DB06091
    Investigational

    TH-302 has been shown, in preclinical studies, to be both efficacious and well tolerated. … TH-302 is a nitroimidazole-linked prodrug of a brominated derivative of an isophosphoramide mustard previously used in cancer drugs such as ifosfamide, cyclophosphamide, and glufosfamide.

    Synonyms: (1-methyl-2-nitro-1H-imidazol-5-YL)methyl N,N'-bis(2-bromoethyl)diamidophosphate, (1-methyl-2-nitro-1H-imidazole-5-yl)methyl N,N'-bis(2-bromoethyl) diamidophosphate