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Plutavimab
go.drugbank.com/drugs/DB18856InvestigationalPlutavimab is under investigation in clinical trial NCT04900428 (Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)).
Categories: Amino Acids, Peptides, and ProteinsEstrone sulfate
go.drugbank.com/drugs/DB04574Approvedcharacteristics, treatment of vaginal atrophy, treatment of some types of breast cancer (particularly in men and postmenopausal women), treatment of prostate cancer and prevention of osteoporosis. … Estrone sulfate (as estropipate) is a form of estrogen.
Mixtures: Esterified Estrogens and Methyltestosterone, Esterified Estrogens and MethyltestosteroneCategories: Hormones, Hormone Substitutes, and Hormone AntagonistsTianeptine
go.drugbank.com/drugs/DB09289InvestigationalAsia (including Singapore) and Latin America as “Stablon” and “Tatinol” but it is not available in Australia, Canada, New Zealand, the U.K. or the U.S. … Currently, tianeptine is approved in France and manufactured and marketed by Laboratories Servier SA; it is also marketed in several other European countries under the trade name “Coaxil” as well as in
Tapinarof
go.drugbank.com/drugs/DB06083ApprovedInvestigationalTapinarof is a novel, first-in-class, small-molecule AhR agonist that is indicated for the treatment of adult psoriasis. … [A248790] Tapinarof received initial approval from the FDA in 2022.[L41845]
Allogeneic processed thymus tissue
go.drugbank.com/drugs/DB16736ApprovedAs part of the immune system, the thymus is an organ responsible for the maturation and selection of T cells [A239814]; thus, patients without a functional thymus experience profound immunodeficiency and … [L38929] Congenital athymia is a rare condition that leads to the absence of a thymus at birth and a high premature mortality rate, with patients typically dying by age two or three.
Lifitegrast
go.drugbank.com/drugs/DB11611ApprovedInvestigationalIt has shown to protect the corneal surface and alleviate the symptoms of dry eye syndrome with fast onset of action and well tolerated profile in both local and systemic setting [A18805]. … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process.
Categories: Amino Acids, Peptides, and Proteins, Compounds used in a research, industrial, or household settingGadoquatrane
go.drugbank.com/drugs/DB33282Approvedin the central nervous system and in the body. … [L63930] Bayer announced FDA approval of gadoquatrane on June 15, 2026, for use with MRI in adult and pediatric patients, including term neonates, to detect and visualize lesions with abnormal vascularity
Idarucizumab
go.drugbank.com/drugs/DB09264ApprovedIdarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its … Its use is associated with immediate, complete and sustained reversal of the anticoagulant effects of dabigatran.
Categories: Amino Acids, Peptides, and ProteinsRepotrectinib
go.drugbank.com/drugs/DB16826ApprovedInvestigationalThis approval is based on favorable results from the TRIDENT-1 study, where the objective response rate was 79% in TKI-naive patients and 38% in TKI-pretreated patients respectively.[L48741] … [A262056] Repotrectinib possesses a compact macrocyclic structure that both limits adverse interactions with resistance mutation hotspots and targets mutations in the solvent-front region.
Categories: Antineoplastic and Immunomodulating AgentsDamoctocog alfa pegol
go.drugbank.com/drugs/DB14700ApprovedInvestigational[L4576,A38909] This product has been engineered by Bayer[L4576] and a biological license application has been filed with the FDA in August 2017 and FDA approved in August 2018.[F1609] … In recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval.