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Displaying results 4051 - 4060 of 10000 in total
  1. Drug

    Metocurine

    go.drugbank.com/drugs/DB01336
    Approved

    Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant. … Patients on chronic anticonvulsant drugs are relatively resistant to metocurine. [A2393]

    Categories: Heterocyclic Compounds, 2-RingSynonyms: O,O-Dimethylchondrocurarine
  2. Drug

    Heptaminol

    go.drugbank.com/drugs/DB13574
    Investigational

    Categories: Vasodilators Used in Cardiac Diseases
  3. Drug

    Propidium

    go.drugbank.com/drugs/DB02166
    Experimental

    Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes … with cholinesterase which it inhibits.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 3-Ring
  4. Drug

    3,3'-diindolylmethane

    go.drugbank.com/drugs/DB11875
    Investigational

    Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-Ring
  5. Drug

    Votucalis

    go.drugbank.com/drugs/DB05032
    Investigational

    rEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.

  6. Drug

    Chromium gluconate

    go.drugbank.com/drugs/DB14528
    Approved

  7. Drug

    Nitrendipine

    go.drugbank.com/drugs/DB01054
    ApprovedWithdrawn

    Nitrendipine is a calcium channel blocker with marked vasodilator action. … It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.

    Mixtures: ENEAS® 10/20 MG COMPRIMIDOS, ENEAS® 10/20 MG COMPRIMIDOSCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  8. Drug

    Dapsone

    go.drugbank.com/drugs/DB00250
    ApprovedInvestigational

    It is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) … Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms.

    Synonyms: 4-(4-aminophenylsulfonyl)aniline, p,p-sulphonylbisbenzamineMixtures: Dapsone 6% / Niacinamide 4%, Dapsone 6% / Niacinamide 2% / Spironolactone 5%
  9. Drug

    Eldecalcitol

    go.drugbank.com/drugs/DB05295
    Investigational

    Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. … Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.

    Synonyms: 1α,25-dihydroxy-2β-(3-hydroxypropoxy)cholecalciferolCategories: Vitamin D and Analogues
  10. Drug

    Cilomilast

    go.drugbank.com/drugs/DB03849
    Investigational

    Following four clinical trials, the drug proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile. … It is orally active and acts as a selective Phosphodiesterase-4 inhibitor.

    Categories: Phosphodiesterase 4 InhibitorsSynonyms: cis-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid