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Gadolinium
go.drugbank.com/drugs/DB12091ApprovedInvestigationalWithdrawnGadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease.
Categories: Compounds used in a research, industrial, or household settingLC16M8
go.drugbank.com/drugs/DB05019InvestigationalIt is the only attenuated vaccine to be licensed for use in humans to prevent smallpox infection.
Cobamamide
go.drugbank.com/drugs/DB11191ApprovedNutraceuticalVitamin B12 is a collective term for these variously substituted corrinoids. … Please refer to the entry [DB00115] for more information on this entry.
Categories: Heterocyclic Compounds with 4 or More RingsDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedA specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Categories: Drugs for Functional Gastrointestinal DisordersNitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approved[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseAdimrSC-2f
go.drugbank.com/drugs/DB16436InvestigationalThe AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine manufacturer with both EU GMP and US FDA certification in Asia[L30553].
XEN-D0101
go.drugbank.com/drugs/DB06020ExperimentalXEN-D0101 is an investigational drug developed by Xention Inc. for the treatment of Atrial Fibrillation. XEN-D0101 works by being a selective antagonist of the voltage-gated potassium channel Kv1.5.
SPC2968
go.drugbank.com/drugs/DB06351InvestigationalSPC2968 is a synthetic antisense oligodeoxynucleotide targeting hypoxia-inducible factor-1alpha (HIF-1alpha). It was under investigation in clinical trial NCT02564614 (A Study of Hypoxia-inducible Factor 1a (HIF1A) Messenger Ribonucleic ...
Aleglitazar
go.drugbank.com/drugs/DB08915InvestigationalAleglitazar is an investigational drug from the company Hoffmann–La Roche and is currently in a phase III clinical trial called ALECARDIO. … It is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity.
Oteracil
go.drugbank.com/drugs/DB03209ApprovedInvestigationalfor continued cancer growth. … It functions by blocking the enzyme orotate phosphoribosyltransferase (OPRT), which is involved in the production of 5-FU.