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Displaying results 4071 - 4080 of 10000 in total
  1. Drug

    Diflorasone

    go.drugbank.com/drugs/DB00223
    Approved

    Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.

  2. Drug

    Lyme disease vaccine (recombinant OspA)

    go.drugbank.com/drugs/DB00045
    ApprovedWithdrawn

    Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant. … Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli.

  3. Drug

    Mito-4509

    go.drugbank.com/drugs/DB05846
    Experimental

    It is used to treat Parkinson's Disease, Alzheimer's Disease, Retinal Disorders and other neurologic Disorders. … Mito-4509 is a non-feminizing estrogen analog that could affect mitochondrial metabolic pathways.

  4. Drug

    Resveratrol

    go.drugbank.com/drugs/DB02709
    Investigational

    Resveratrol (3,5,4'-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase. … However, studies find that Trans-resveratrol undergoes negligible oxidation in normal atmosphere at room temperature.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Adenosine phosphate

    go.drugbank.com/drugs/DB00131
    ApprovedInvestigationalNutraceuticalWithdrawn

    Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]

  6. Drug

    Seletracetam

    go.drugbank.com/drugs/DB05885
    Investigational

    It is predicted to have low drug-drug interactions and inhibition or induction of any major human metabolizing enzymes. Seletracetam was in Phase II clinical trials under the supervision of the U.S. … Food and Drug Administration (FDA) investigated as treatment of epilepsy and partial epilepsy however its development had been put on hold in July 2007.

  7. Drug

    JSM 6427

    go.drugbank.com/drugs/DB06139
    Investigational

    It has been biologically validated for therapeutic use in the prevention and treatment of wet AMD, the leading cause of blindness in people over the age of 55. … JSM 6427 is the first small molecule alpha5beta1 integrin receptor antagonist of its kind to be developed.

  8. Drug

    Denufosol

    go.drugbank.com/drugs/DB04983
    Investigational

    A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial showed a lack of improvement in lung function for cystic fibrosis patients taking denufosol. … Denufosol was an inhaled drug used for the treatment of cystic fibrosis (CF), showing various improvements in lung function during a phase III clinical trial.

  9. Drug

    Carbomer homopolymer type C

    go.drugbank.com/drugs/DB14091
    Investigational

    Carbomer homopolymer type C is a high molecular polyanionic substance tested for antiulcerogenic activity.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Domiphen

    go.drugbank.com/drugs/DB11594
    Approved

    Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.

    Synonyms: Domiphen ion, 1-dodecanaminium, n,n-dimethyl-n-(2-phenoxyethyl)