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Displaying results 4071 - 4080 of 10000 in total
  1. Drug

    XL281

    go.drugbank.com/drugs/DB05190
    Investigational

    XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which is activated in 60 percent of melanomas, 24-44 percent of thyroid cancers, and 9 percent of colon cancers. … Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer.

  2. Drug

    Sulfamethazine

    go.drugbank.com/drugs/DB01582
    ApprovedVet approvedWithdrawn

    It has a spectrum of antimicrobial action similar to other sulfonamides.

    Synonyms: N-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide, N(1)-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide
  3. Drug

    Talactoferrin alfa

    go.drugbank.com/drugs/DB05426
    Investigational

    Talactoferrin alfa is a novel immunomodulatory 80 kD protein with demonstrated oral anti-tumor properties. Lactoferrin, a protein found in breast milk is developed by Agennix. … It increases body’s immune power and also works as a natural antioxidant, helping to control cell and tissue damage caused by oxidation.

  4. Drug

    Chlorotoxin I-131

    go.drugbank.com/drugs/DB05462
    Investigational

    Chlorotoxin I-131 is investigated in clinical trials for treating brain cancer. … The synthetic version of this peptide has been manufactured and covalently linked to iodine 131 as a means of targeting radiation to tumor cells in the treatment of brain cancer.

    Synonyms: I(131)-TM-601 (chlorotoxin)
  5. Drug

    Calcium cation

    go.drugbank.com/drugs/DB14577
    Investigational

    Synonyms: calcium(2+) ionMixtures: POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 1000 CC SETLI, POLİFLEKS LAKTATLI RİNGER IV İNFÜZYON İÇİN ÇÖZELTİ, 1000 CC SETSİZ
  6. Drug

    Dextranomer

    go.drugbank.com/drugs/DB13560
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Famphur

    go.drugbank.com/drugs/DB11408
    ExperimentalVet approved

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Bizelesin

    go.drugbank.com/drugs/DB12352
    Investigational

    Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Carfentanil

    go.drugbank.com/drugs/DB01535
    IllicitInvestigationalVet approved

    Carfentanil is intended for large-animal use only as its extreme potency makes it inappropriate for use in humans. … It has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl, with activity in humans starting at about 1 microgram.

  10. Drug

    Pozelimab

    go.drugbank.com/drugs/DB15218
    ApprovedInvestigational

    autoimmune hemolysis that are often observed in CHAPLE disease. … CD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US.