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Displaying results 401 - 410 of 10000 in total
  1. Drug

    Pimozide

    go.drugbank.com/drugs/DB01100
    Approved

    A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. … Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)

    Products: PMS-pimozide
  2. Drug

    Menotropins

    go.drugbank.com/drugs/DB00032
    ApprovedInvestigational

    It is used as a fertility medication that is injected either subcutaneously or intramuscularly.

    Products: Meriofert PFS 75 I.E. Pulver und Lösungsmittel zur Herstellung einer Injektionslösung, Meriofert PFS 150 I.E. Pulver und Lösungsmittel zur Herstellung einer Injektionslösung
  3. Drug

    Antithrombin III human

    go.drugbank.com/drugs/DB11598
    ApprovedInvestigational

    A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

    Products: Thrombate III Pws IV 500iu/vial, Thrombate III Pws IV 1000iu/vial
  4. Drug

    Thiamine

    go.drugbank.com/drugs/DB00152
    ApprovedInvestigationalNutraceuticalVet approved

    Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. … Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated.

    Mixtures: Vita-Pac, Children's Chew Multi & Min TabProducts: /ML)EN FRASCOAMPOLLA POR 10 ML
  5. Drug

    Methadone

    go.drugbank.com/drugs/DB00333
    ApprovedInvestigational

    [A185888,A185891,A185897] Compared with [morphine], the gold standard reference opioid, methadone also acts as an agonist of κ- and σ-opioid receptors, as an antagonist of the N-methyl-D-aspartate (NMDA … ) receptor, and as an inhibitor of serotonin and norepinephrine uptake.

    Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersProducts: PMS-methadone, PMS-methadone Hydrochloride Oral Concentrate
  6. Drug

    Ertapenem

    go.drugbank.com/drugs/DB00303
    ApprovedInvestigational

    [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002.

    Synonyms: (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acidProducts: Ertapenem AptaPharma 1 g Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Ertapenem Panpharma 1 g Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  7. Drug

    Hydroxyzine

    go.drugbank.com/drugs/DB00557
    ApprovedInvestigational

    [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.

    Products: PMS Hydroxyzine Cap 10mg, PMS Hydroxyzine Cap 50mg
  8. Drug

    Oxycodone

    go.drugbank.com/drugs/DB00497
    ApprovedIllicitInvestigational

    [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics … [Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]

    Mixtures: PMS-oxycodone - Acetaminophen, OSSICODONE E NALOXONE EGProducts: PMS-oxycodone, PMS-oxycodone CR
  9. Drug

    Hydroxocobalamin

    go.drugbank.com/drugs/DB00200
    ApprovedInvestigational

    Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.

    Products: VITAMIN B12 DEP PAN 1000UG
  10. Drug

    Oxtriphylline

    go.drugbank.com/drugs/DB01303
    Approved

    Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. … In the US, oxtriphylline is no longer available.

    Mixtures: PMS-oxtriphylline ElixirProducts: PMS Oxtriphylline Syr Pediatric 10mg/ml