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Desvenlafaxine
go.drugbank.com/drugs/DB06700ApprovedInvestigationalThe major difference is the potential for drug interaction since venlafaxine is mainly metabolized by CYP2D6 while desvenlafaxine is conjugated by UGT; therefore, desvenlafaxine is less likely to cause … Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of [venlafaxine].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesSynonyms: O-desmethylvenlafaxineBaclofen
go.drugbank.com/drugs/DB00181ApprovedInvestigationalAlthough originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. … [A245323, A245338] Baclofen is used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and traumatic brain injury.
Mixtures: Innoprax-5Products: LIORESAL 10 MG TABLET, 50 ADET, COLMIFEN 10 TABLET 10 mgRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalHowever there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: XARELTO 10 MG FILM KAPLI TABLET, 100 ADET, VOXABAN 10 MG FİLM KAPLI TABLET, 100 ADETErdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalErdosteine has been shown to be safe and well tolerated in clinical trials. … Three active metabolites result and possess mucolytic activity in addition to free radical scavenging activity.
Products: ENZEVİN 175 MG/5 ML SUSPANSIYON ICIN KURU TOZ, 100 ML, EVOSTEN 175 MG/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 100 MLFlucloxacillin
go.drugbank.com/drugs/DB00301ApprovedInvestigationalWithdrawnAntibiotic analog of cloxacillin.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillinSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A242372] In November 2000, the drug was recognized by the European Agency as an alternative to calcineurin antagonists for maintenance therapy with corticosteroids. … rapamycin (mTOR), which is a serine/threonine-specific protein kinase that regulates cell growth, proliferation, and survival. mTOR is an important therapeutic target for various diseases, as it was shown to
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: RAPAMUNE 1 MG 100 FILM DRAJE, RAPAMUNE 0.5 MG TABLET ,100 ADETMethylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalHistorically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered the market. … clinical trials to be an inhibitor of Tau protein aggregation.
Mixtures: Urimar-T, Urimar-TCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 CYP1A2 InducersEstramustine
go.drugbank.com/drugs/DB01196ApprovedWithdrawnA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ESTRACYT 300 MG ENJEKTABL FLAKON, 10 ADET, ESTRACYT 140 MG KAPSUL, 100 ADETAvena sativa pollen
go.drugbank.com/drugs/DB10377ApprovedAvena sativa pollen is the pollen of the Avena sativa plant. Avena sativa pollen is mainly used in allergenic testing.
Synonyms: Avena sativa pollenProducts: Center-AL - Avena Sativa Pollen, Pollens - Grasses, Oats, Common, Cultivated Avena sativaRiboflavin
go.drugbank.com/drugs/DB00140ApprovedInvestigationalNutraceuticalVet approvedNutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms ...
Mixtures: NEUVITAN 50 MG/ 5 ML KAPLI TABLET, 50 ADET, Multivitamin with 1.0 mg FluorideSynonyms: 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol, 7,8-Dimethyl-10-ribitylisoalloxazine