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Displaying results 4101 - 4110 of 10000 in total
  1. Drug

    Enarodustat

    go.drugbank.com/drugs/DB14985
    Investigational

    Enarodustat is under investigation in clinical trial NCT02581124 (Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease).

  2. Drug

    XL281

    go.drugbank.com/drugs/DB05190
    Investigational

    Mutational activation of RAS occurs in about 30 percent of all human tumors, including non-small cell lung, pancreatic, and colon cancer. … XL281 is a specific inhibitor of RAF kinases, including the mutant form of B-RAF, which is activated in 60 percent of melanomas, 24-44 percent of thyroid cancers, and 9 percent of colon cancers.

  3. Drug

    Diloxanide furoate

    go.drugbank.com/drugs/DB14638
    ApprovedInvestigational

    Synonyms: 2,2-dichloroacetamido-4-n-methylphenyl 2-furoate, 4-(n-methyl-2,2-dichloroacetamido)phenyl 2-furoate
  4. Drug

    Bimakalim

    go.drugbank.com/drugs/DB19948
    Experimental

    The usage of the INN stem '-kalim' in the name indicates that Bimakalim is a potassium channel activator, antihypertensive. Bimakalim has a monoisotopic molecular weight of 278.11 Da.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Bimoclomol

    go.drugbank.com/drugs/DB06258
    Experimental

    Bimoclomol is an investigational drug that induces stress proteins and has cytoprotective effects.

  6. Drug

    Tezosentan

    go.drugbank.com/drugs/DB06558
    Investigational

    Tezosentan is an intravenous endothelin receptor A/B antagonist. … Tezosentan was initially developed for vasodilation in patients with acute heart failure but studies have shown that it does not assist in the treatment of dyspnea or prevent cardiovascular events.

  7. Drug

    Tavaborole

    go.drugbank.com/drugs/DB09041
    Approved

    Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).

  8. Drug

    Morrhuic acid

    go.drugbank.com/drugs/DB14087
    Investigational

    Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil.

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Sulfamoxole

    go.drugbank.com/drugs/DB08798
    Experimental

    Sulfamoxole is an antibacterial in the sulfonamide class.

    Synonyms: N(sup 1)-(4,5-Dimethyl-2-oxazolyl)sulfanilamide, 4-Amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamide
  10. Drug

    Detomidine

    go.drugbank.com/drugs/DB11556
    InvestigationalVet approved

    Currently, it is only approved by the FDA for use in horses but has been studied for use in other large animals. … Detomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride.