Search

Displaying results 4101 - 4110 of 4188 in total
  1. Drug

    Ceftiofur

    go.drugbank.com/drugs/DB11485
    ExperimentalVet approved

    E. coli strains resistant to ceftiofur have been reported.

  2. Drug

    H3B-8800

    go.drugbank.com/drugs/DB14017
    Investigational

    H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine . It offers the benefit of preferentially killing spliceosome-mutant cancer cells whereas other splicesome inhibitors, such as the pladienolide analogue E7107, show no...

  3. Drug

    Ivarmacitinib

    go.drugbank.com/drugs/DB16756
    Investigational

    Ivarmacitinib (SHR0302) is a selective inhibitor of Janus kinase 1 (JAK1) under investigation for the treatment of various immuno-inflammatory conditions. While ivarmactinib has yet to receive marketing authorization, as of February 2022...

  4. Drug

    Maxy-G34

    go.drugbank.com/drugs/DB05718
    Investigational

    lysines have been removed as compared to wild type human G-CSF to avoid PEGylation of such sites. … This variant contains multiple non-naturally occurring lysines that have been introduced into alpha helixes of wild type human G-CSF as PEGylation sites, and from which multiple undesired, naturally occurring

  5. Target

    Voltage-gated inwardly rectifying potassium channel KCNH2

    go.drugbank.com/bio_entities/BE0000090
    TargetTransporterHumans

    Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel (PubMed:10219239, PubMed:10753933, PubMed:10790218, PubMed:10837251, PubMed:11997281, PubMed:12063277, PubMed:18559421, PubMed:22314138, PubMed:22359612,...

    Synonyms: Ether-a-go-go-related gene potassium channel 1
  6. Drug

    MX6

    go.drugbank.com/drugs/DB05789
    Experimental

    More specifically, it has been shown that such adamantyl compounds, e.g., 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid, 2-[3-(1-adamantyl)-4-methoxyphenyl]-5-benzimidazole carboxylic acid, and

  7. Drug

    AICA ribonucleotide

    go.drugbank.com/drugs/DB01700
    Investigational

    AICAR has been used clinically to treat and protect against cardiac ischemic injury.

  8. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to infl...

  9. Drug

    Robenidine

    go.drugbank.com/drugs/DB11542
    ExperimentalVet approved

    Despite the availability of other agents to treat coccidiosis, robenidine has been proven to be effective in delaying the development of antibiotic resistance through intermittent and rotating use with

  10. Drug

    Cipepofol

    go.drugbank.com/drugs/DB16295
    ApprovedInvestigational

    alkylphenol scaffold, with the stated aim of retaining the rapid onset and complete recovery expected of this class of anesthetics while reducing the injection pain and respiratory depression that have long been