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Displaying results 4101 - 4110 of 10000 in total
  1. Target

    Apolipoprotein A-I

    go.drugbank.com/bio_entities/BE0003449
    CarrierTargetEnzymeHumans

    Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase

    Polypeptides: Apolipoprotein A-I
  2. Target

    Prelamin-A/C

    go.drugbank.com/bio_entities/BE0010877
    TargetHumans

    Lamins are intermediate filament proteins that assemble into a filamentous meshwork, and which constitute the major components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner … Lamin A and C also regulate matrix stiffness by conferring nuclear mechanical properties (PubMed:23990565, PubMed:25127216).

    Polypeptides: Prelamin-A/C
  3. Drug

    Gadoversetamide

    go.drugbank.com/drugs/DB00538
    Approved

    Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.

    Categories: Compounds used in a research, industrial, or household settingProducts: CIPROFLOXACINA 100 MG / 10 ML, OPTIMARK 500 MIKROMOL/ML IV. ENJ. ICIN COZ. ICEREN FLAKON, 10 ML
  4. Drug

    Carboxymethylcellulose

    go.drugbank.com/drugs/DB11059
    ApprovedInvestigational

    It is added in food products as a viscosity modifier or thickener and emulsifier. … Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups.

    Mixtures: OPTIVE ®, OPTIVE ®Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Xylometazoline

    go.drugbank.com/drugs/DB06694
    Approved

    Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity.

    Mixtures: Ophtrivin A Ophthalmic Dps, NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADETCategories: Adrenergic alpha-1 Receptor Agonists, Heterocyclic Compounds, 1-Ring
  6. Drug

    Nimesulide

    go.drugbank.com/drugs/DB04743
    ApprovedWithdrawn

    Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. … Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries.

    Mixtures: ETNA COMBO 100 MG/8 MG TABLET, 14 ADET, NİMES COMBO 100 MG / 8 MG TABLET , 14 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Target

    Probable arabinosyltransferase A

    go.drugbank.com/bio_entities/BE0000034
    TargetMycobacterium tuberculosis

    Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.

    Polypeptides: Probable arabinosyltransferase A
  8. Target

    Aurora kinase A

    go.drugbank.com/bio_entities/BE0000991
    TargetHumans

    Plays a role in microtubule remodeling during neurite extension (PubMed:19668197). … Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome

    Polypeptides: Aurora kinase ASynonyms: Serine/threonine-protein kinase aurora-A
  9. Target

    Bacteriochlorophyll a protein

    go.drugbank.com/bio_entities/BE0001362
    TargetChlorobium tepidum (strain ATCC 49652 / DSM 12025 / TLS)

    Intermediary in the transfer of excitation energy from the chlorophyll to the reaction centers.

    Polypeptides: Bacteriochlorophyll a protein
  10. Target

    Beta-glucosidase A

    go.drugbank.com/bio_entities/BE0001810
    TargetEnzymeThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: Beta-glucosidase A