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Y-27632
go.drugbank.com/drugs/DB08756InvestigationalIt inhibits calcium sensitization to affect smooth muscle relaxation.
Echinomycin
go.drugbank.com/drugs/DB15582ExperimentalEchinomycin is a cytotoxic polypeptide quinoxaline antibiotic isolated from _Streptomyces echinatus_ that binds to DNA and inhibits RNA synthesis.
Orismilast
go.drugbank.com/drugs/DB19042InvestigationalOrismilast is under investigation in clinical trial NCT05190419 (Study to Assess the Efficacy and Safety of Orismilast in Psoriasis).
Letolizumab
go.drugbank.com/drugs/DB19072InvestigationalLetolizumab is under investigation in clinical trial NCT02273960 (Study to Evaluate Safety and Efficacy in Adult Subjects With ITP).
SCIB1
go.drugbank.com/drugs/DB18439InvestigationalIt consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate the patient's T cells to have a stronger reaction against melanoma cells.
PHB-050
go.drugbank.com/drugs/DB32061ExperimentalPHB-050 is a novel, next-generation anti-IgE antibody designed to block IgE from binding to mast cells, while also rapidly reducing circulating IgE and inhibiting its production.
Carbon black
go.drugbank.com/drugs/DB11980Investigational[A263401] Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue [A263401] and has been linked to carcinogenicity.[A263406, A263411, A263416]
Synonyms: DC BLACK NO. 2, D&C black no. 2N-(3-carboxypropanoyl)-L-norvaline
go.drugbank.com/drugs/DB08554ExperimentalThis medication is known to target n-acetylornithine carbamoyltransferase and putative ornithine carbamoyltransferase. … This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at his terminal nitrogen atom.
Sitimagene ceradenovec
go.drugbank.com/drugs/DB04907ExperimentalSitimagene ceradenovec is a novel gene-based product for the treatment of patients with operable high grade glioma, a type of malignant brain tumour, given in addition to standard surgery and radiotherapy
Dental Mesenchymal Pulp Stem Cells
go.drugbank.com/drugs/DB15737InvestigationalThese cells have innate neurogenic potential as their origins are traced to the embryonic neural crest; there is potential for these cells to create neurons and glial cells. … In addition, they are able to differentiate into chondrocytes, adipocytes, and odontoblasts under appropriate conditions.