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Conivaptan
go.drugbank.com/drugs/DB00872ApprovedConivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2). … Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin).
Synonyms: 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilideCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsp-tert-Butylphenol-formaldehyde resin (low molecular weight)
go.drugbank.com/drugs/DB14190ApprovedSensitivity to p-tert-Butylphenol-formaldehyde resin may be identified with a clinical patch test. … p-tert-Butylphenol-formaldehyde resin is a widely used adhesive chemical used in a wide variety of commercially available products and a known dermatological sensitizer and allergen [A34290,A34291].
Synonyms: p-tert-Butylphenol-formaldehyde resin (low molecular weight)Corticorelin ovine triflutate
go.drugbank.com/drugs/DB09067ApprovedIt is used as a diagnostic agent to evaluate the status of the pituitary-adrenal axis in the differentiation of a pituitary source from an ectopic source of excessive ACTH secretion. … Endogenous forms hCRH are involved in the stress response and its main function is stimulation of the pituitary to release ACTH.
Synonyms: Sheep corticotropin-releasing factor (1-41)Methoxy polyethylene glycol-epoetin beta
go.drugbank.com/drugs/DB09107ApprovedInvestigationalESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia. … Methoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin.
Categories: Compounds used in a research, industrial, or household settingProducts: MIRCERA 360 MCG/0.6 ML SC/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, MIRCERA 100 MCG/ML SC/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADETRomidepsin
go.drugbank.com/drugs/DB06176ApprovedInvestigationalRomidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSerplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalSerplulimab is a humanized monoclonal IgG4 antibody that acts as an immune checkpoint inhibitor by targeting the programmed cell death-1 (PD-1) receptor. … Most recently, it was approved in the EU in February 2025 for the treatment of extensive-stage small cell lung cancer.[L52968,L52953]
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsSynonyms: Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa.Interferon beta-1a
go.drugbank.com/drugs/DB00060ApprovedInvestigationalThe amino acid sequence is identical to that of natural human interferon beta. … It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced.
Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: Interferon beta 1-a, IFN β-1aGuanidine
go.drugbank.com/drugs/DB00536Approved(From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC. … A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism.
Categories: MATE 1 Substrates, MATE 2 SubstratesNonivamide
go.drugbank.com/drugs/DB11324ApprovedNonivamide is found in herbs and spices. It is an alkaloid from the Capsicum species. … The structures of [DB06774] and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus nonanoic acid) [F31].
Mixtures: Nonivamid + Nicoboxil Zentiva 4 mg/g + 25 mg/g SalbeSynonyms: N-Vanillylnonamide, N-Nonanoyl vanillylamidePractolol
go.drugbank.com/drugs/DB01297ApprovedA beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsSynonyms: 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol, N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide