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Displaying results 4141 - 4150 of 10000 in total
  1. Target

    Tubulin beta-6 chain

    go.drugbank.com/bio_entities/BE0003402
    TargetHumans

    Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microt...

    Polypeptides: Tubulin beta-6 chain
  2. Target

    6-phosphogluconate dehydrogenase, decarboxylating

    go.drugbank.com/bio_entities/BE0003559
    TargetEnzymeHumans

    Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH

    Polypeptides: 6-phosphogluconate dehydrogenase, decarboxylating
  3. Target

    ADP-ribosylation factor 6

    go.drugbank.com/bio_entities/BE0004242
    TargetHumans

    GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (PubMed:11266366, PubMed:16737952, PubMed:18400762, PubMed:21170023, PubMed:32103017, PubMed:7589240). GTP-bound form play...

    Polypeptides: ADP-ribosylation factor 6
  4. Target

    Protein-tyrosine kinase 6

    go.drugbank.com/bio_entities/BE0004731
    TargetHumans

    Non-receptor tyrosine-protein kinase implicated in the regulation of a variety of signaling pathways that control the differentiation and maintenance of normal epithelia, as well as tumor growth. Function seems to be context dependent an...

    Polypeptides: Protein-tyrosine kinase 6
  5. Target

    Toll-like receptor 6

    go.drugbank.com/bio_entities/BE0010079
    TargetHumans

    Participates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides (PubMed:20037584). In response to diacylated lipopeptides, forms the act...

    Polypeptides: Toll-like receptor 6
  6. Target

    Seizure protein 6 homolog

    go.drugbank.com/bio_entities/BE0014836
    TargetHumans

    May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor...

    Polypeptides: Seizure protein 6 homologSynonyms: SEZ-6, hSEZ-6
  7. Drug

    Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborate

    go.drugbank.com/drugs/DB14106
    ApprovedInvestigational

    Tetrakis (2-methoxyisobutylisocyanide) copper (I) tetrafluoroborate is a component of Cardiolite, a technetium Tc99m-based imaging agent used for assessing myocardial perfusion.[L12744]

    Synonyms: Tetrakis (2-methoxyisobutyl isonitrile) copper (I) tetrafluoroborate, Tetrakis(2-methoxyisobutylisocyanide)copper(I) tetrafluoroborateProducts: MIBITEC 1 mg Kit für ein radioaktives Arzneimittel, CardioTOP 1 mg Kit für ein radioaktives Arzneimittel
  8. Drug

    Lorigerlimab

    go.drugbank.com/drugs/DB18942
    Investigational

    Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).

    Synonyms: MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC,, -CHAIN V-J REGION) FUSION PROTEIN WITH PEPTIDE LINKER (GGGSGGGG) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEI
  9. Drug

    Chloramphenicol

    go.drugbank.com/drugs/DB00446
    ApprovedInvestigationalVet approvedWithdrawn

    It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. … An antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically.

    Mixtures: CORTIFENOL H POMADA OFTALMICA 4 G, CLOXONA-OCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP2C19 Inhibitors
  10. Drug

    Octasulfur

    go.drugbank.com/drugs/DB09353
    Approved

    Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). … After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli.

    Mixtures: SulfaCleanse 8/4, Sulfatol 10-4 Cleansing padsProducts: 111MedCo 6% Sulfur Skin Cleansing Bar, Acne All-Star 3-in-1 Acne Cleanser, Mask and Spot Treatment