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Displaying results 4141 - 4150 of 10000 in total
  1. Drug

    mRNA-1010

    go.drugbank.com/drugs/DB22484
    Approved

    benefit to be confirmed in a postmarketing trial. … [L64058] The FDA approved mFLUSIVA on August 5, 2026 for active immunization against influenza in adults 50 years of age and older, making it the first mRNA-based influenza vaccine approved in the United

    Categories: Complex Mixtures
  2. Drug

    Efbemalenograstim alfa

    go.drugbank.com/drugs/DB18704
    ApprovedInvestigational

    This approval was contingent on positive results observed in two pivotal Phase 3 Studies GC-627-04 and GC-627-05 in the US and Europe respectively.[L48887] … [A33650,A262172] On November 22, 2023, efbemalenograstim alfa was approved by the FDA under the brand name Ryzneuta for the treatment of chemotherapy-induced neutropenia in adult patients with non-myeloid

    Synonyms: Rh g-csf fc fusion protein f-627, Recombinant dimeric g-csf fusion protein f627
  3. Drug

    Iodide I-123

    go.drugbank.com/drugs/DB09420
    ApprovedInvestigational

    Radioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared … Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease.

  4. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

    go.drugbank.com/bio_entities/BE0000367
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis (PubMed:27626371, PubMed:32385911, PubMed:33153867). … Complex I functions in the transfer of electrons from NADH to the respiratory chain (PubMed:27626371). The immediate electron acceptor for the enzyme is believed to be ubiquinone (PubMed:27626371)

    Synonyms: Complex I-19kD, Complex I-PGIV
  5. Drug

    Calcium glucoheptonate

    go.drugbank.com/drugs/DB00326
    ApprovedInvestigational

    Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. … They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body needs calcium to make strong bones.

  6. Drug

    Tempol

    go.drugbank.com/drugs/DB12449
    Investigational

    Tempol has been used in trials studying the treatment of Anal Cancer.

    Categories: Compounds used in a research, industrial, or household setting, Spin LabelsSynonyms: 4-Hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl
  7. Drug

    Benzyl alcohol

    go.drugbank.com/drugs/DB06770
    ApprovedInvestigational

    Mixtures: BEHEPTAL 20 DRAJE, Fast Freeze Lidocaine Roll-On
  8. Drug

    Canertinib

    go.drugbank.com/drugs/DB05424
    Investigational

    Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo.

    Categories: Compounds used in a research, industrial, or household setting
  9. Indication

    Migraine With Aura

    go.drugbank.com/conditions/DBCOND0031385
    Drugs: Eletriptan · Frovatriptan · Meloxicam · Rimegepant · Rizatriptan · Ubrogepant
    Synonyms: Complex migraine
  10. Drug

    Vepdegestrant

    go.drugbank.com/drugs/DB19006
    ApprovedInvestigational

    [A275507, A275509] In a global, randomized Phase III clinical trial (VERITAC-2), vepdegestrant was clinically evaluated and compared against the injectable selective estrogen receptor degrader (SERD) [ … [A275508] Specifically, vepdegestrant is being developed as a first-line or subsequent treatment option for patients whose tumors grow in response to estrogen and have progressed after standard therapies