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Pregnenolone
go.drugbank.com/drugs/DB02789ApprovedInvestigationalWithdrawnA 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLanadelumab
go.drugbank.com/drugs/DB14597ApprovedInvestigational[A38676] Lanadelumab was approved for use in patients with hereditary angioedema by the FDA in August 2018,[L4537] followed by Health Canada in October 2018[L49226] and the EMA in November 2018. … Lanadelumab, also known as DX-2930, is a human IgG1 monoclonal antibody designed for subcutaneous self-injection.
Products: TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, TAKHZYRO 300 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADETBirch bark extract
go.drugbank.com/drugs/DB16536ApprovedInvestigational[L42390] Filsuvez was subsequently approved for the same indication by the US FDA in December 2023. … [L42365,L42370] Filsuvez, one of these two formulations, is approved for the treatment of partial thickness wounds in patients with epidermolysis bullosa (EB), a rare group of hereditary disorders of the
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme InhibitorsFenofibric acid
go.drugbank.com/drugs/DB13873ApprovedInvestigationalIt works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol. … [A32038,L12855] Due to its high hydrophilicity and poor absorption profile,[A32038] prodrug ,[fenofibrate], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed
Mixtures: STAFEN®135 / 5 MG CAPSULAS, FENOVAS®20 MGProducts: TRILIPIX®135MG, NORMOLIP NF® 135MG CÁPSULAMefenamic acid
go.drugbank.com/drugs/DB00784ApprovedA non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: N-(2,3-xylyl)-2-aminobenzoic acid, N-2,3-xylylanthranilic acidEtifoxine
go.drugbank.com/drugs/DB08986ApprovedWithdrawnIt does not bind to the benzodiazepine receptor though the effects are similar to that of benzodiazepines. It is more effective than lorazepam as an anxiolytic, and has fewer side effects. … Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing.
Categories: Heterocyclic Compounds, 1-RingProducts: EXSIST® CAPSULASXEN-2174
go.drugbank.com/drugs/DB05012ExperimentalXEN-2174 is a synthetic drug modeled on a peptide from the venom of a cone shell found on Australia's Great Barrier Reef. … NET is the primary mechanism regulating the biological effects of norepinephrine (NE) on the body.
Embusartan
go.drugbank.com/drugs/DB19949ExperimentalEmbusartan is a small molecule drug. The usage of the INN stem '-sartan' in the name indicates that Embusartan is a angiotensin II receptor antagonist, antihypertensive (non-peptidic). … Embusartan has a monoisotopic molecular weight of 461.19 Da.
Categories: Agents Acting on the Renin-Angiotensin System, Heterocyclic Compounds, 1-RingEthiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalEthiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. … And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown.
Categories: X-Ray Contrast Activity, X-Ray Contrast Media, IodinatedProducts: LIPIODOL ® ULTRA-FLUIDE, LİPİODUL ULTRA-FLUİD 480 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ , 5 MLTrandolaprilat
go.drugbank.com/drugs/DB14209ExperimentalThe active metabolite of the prodrug [Trandolapril].
Categories: Agents Acting on the Renin-Angiotensin System, Heterocyclic Compounds, 2-Ring