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Estradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedBecause of the difference in potency between estradiol and estrone, menopause (and a change in primary hormone from estradiol to estrone) is associated with a number of symptoms associated with this reduction … in potency and in estrogenic effects.
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A1 SubstratesSynonyms: Estradiol 3-acetate, Estradiol-3-acetateGrapiprant
go.drugbank.com/drugs/DB12836InvestigationalVet approved[A39838] This type of molecules is currently in development for veterinary patients.[A39816] This class of drugs was defined in 2013 by the World Health Organization. … [L4766] Grapiprant has been approved in March 2016 by the FDA's Center for Veterinary Medicine as a non-cyclooxygenase inhibiting NSAID for veterinary use.[A39836]
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingFluoroazomycin arabinoside F-18
go.drugbank.com/drugs/DB15134InvestigationalFluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer).
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: FAZA F-18, Fluoroazomycin arabinoside F-18Sar9, Met (O2)11-Substance P
go.drugbank.com/drugs/DB05875InvestigationalIt is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species. … Sar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist.
Categories: Receptors, Neurokinin-3, antagonists & inhibitorsSynonyms: 9-Sar-substance P sulfone, 9-Sar-11-met(O2)-substance PElsamitrucin
go.drugbank.com/drugs/DB05129InvestigationalThe cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor models of murine and human origin. (PMID: 8150873)
Nigericin
go.drugbank.com/drugs/DB14056ExperimentalA polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. (From Merck Index, 11th ed)
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: Helixin C, Azalomycin MSSR-126517E
go.drugbank.com/drugs/DB05362ExperimentalSSR-126517E is a second generation synthetic pentasaccharide that binds antithrombin with such high affinity that it assumes a plasma half-life of 80 hours.
Rotenone
go.drugbank.com/drugs/DB11457ExperimentalVet approvedRotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: 5'β-rotenone, [2R-(2α,6aα,12aα)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one2-Undecanone
go.drugbank.com/drugs/DB08688ExperimentalCategories: Compounds used in a research, industrial, or household settingSynonyms: 2-hendecanone, Undecan-2-one