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Displaying results 4161 - 4170 of 10000 in total
  1. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation. … A competitive serotonin type 3 receptor antagonist.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: ZOFRAN INJECTION 2 mg/ml, ZOPHRALEN 4 MG/2 ML IV AMPUL, 5 ADET
  2. Drug

    Berbamine

    go.drugbank.com/drugs/DB18146
    Experimental

    Synonyms: 16h-1,24:6,9-dietheno-11,15-metheno-2h-pyrido(2',3':17,18)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolin-12-ol, 3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4as-(4ar*,16as*))-, 16h-1,24:6,9-dietheno-11,15-metheno-2h-pyrido(2',3':17,18)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolin-12-ol, 3,4,4a,5,16a,17,18,19-octahydro-21,22,26-trimethoxy-4,17-dimethyl-, (4as,16ar)-Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Farnesyl diphosphate

    go.drugbank.com/drugs/DB07780
    Experimental

    Synonyms: 2-trans,6-trans-farnesyl diphosphate, (2E,6E)-farnesol diphosphate
  4. Drug

    (S)-alpha-methyl-4-carboxyphenylglycine

    go.drugbank.com/drugs/DB04256
    Experimental

    Synonyms: (S)-(+)-α-amino-4-carboxy-2-methylbenzeneacetic, (S)-a-methyl-4-carboxyphenylglycine
  5. Drug

    AKV-9

    go.drugbank.com/drugs/DB18061
    Experimental

    Synonyms: 5-((S)-1-(3,5-bis(trifluoromethyl)phenoxy)ethyl)-3-hydroxycyclohex-2-en-1-one, 1,3-Cyclohexanedione, 5-[(1S)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]-
  6. Drug

    Gentamicin

    go.drugbank.com/drugs/DB00798
    ApprovedInvestigationalVet approved

    Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity

    International brands: G-Mycin, U-gencinMixtures: GENTAMICINA 0.1% + DEXAMETASONA 0.04% + KETOCONAZOL 2% CREMA, INDOBIOTIC GOZ DAMLASI, 5 ML
  7. Drug

    Beludavimab

    go.drugbank.com/drugs/DB18952
    Investigational

    Beludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).

    Synonyms: IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONAL, VIR-7832 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOC
  8. Drug

    Bavdegalutamide

    go.drugbank.com/drugs/DB19032
    Investigational

    Bavdegalutamide is under investigation in clinical trial NCT03888612 (Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer).

    Synonyms: 3-pyridazinecarboxamide, n-(trans-4-(3-chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxo-3-piperidinyl)-6-fluoro-2,3-dihydro-1,3-dioxo-1h-isoindol-5-yl)-1-piperazinyl)methyl)-1-piperidinyl)-, N-((1r,4r)-4-(3-chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxo-2,3-dihydro-1h-isoindol-5-yl)piperazin-1-yl)methyl)piperidin-1-yl)pyridazine-3-carboxamide
  9. Drug

    Haloperidol

    go.drugbank.com/drugs/DB00502
    ApprovedInvestigational

    (mainly D2), particularly within the mesolimbic and mesocortical systems of the brain. … Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one
  10. Drug

    Busulfan

    go.drugbank.com/drugs/DB01008
    ApprovedInvestigational

    Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.

    Synonyms: 1, 4-Bis[methanesulfonoxy]butaneCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 Substrates