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Displaying results 411 - 420 of 3180 in total
  1. Drug

    Lamotrigine

    go.drugbank.com/drugs/DB00555
    ApprovedInvestigational

    Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Dru...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Nu-lamotrigine
  2. Drug

    Aluminum zirconium tetrachlorohydrex gly

    go.drugbank.com/drugs/DB11149
    ApprovedWithdrawn

    Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat...

    Products: No Name Ladies Antip 23% Sport Scent, Big V Stk A/p Scented 22%
  3. Drug

    Calcium chloride

    go.drugbank.com/drugs/DB01164
    ApprovedInvestigational

    Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applicat...

    Mixtures: Vamin N, SOLUCION RINGER NO.3
  4. Drug

    Vericiguat

    go.drugbank.com/drugs/DB15456
    ApprovedInvestigational

    cell types) that catalyze the synthesis of cyclic guanosine monophosphate (cGMP) in response to activation by nitric oxide (NO). … [L31153] A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst other

    Categories: P-glycoprotein substrates
  5. Drug

    Turoctocog alfa pegol

    go.drugbank.com/drugs/DB14738
    ApprovedInvestigational

    N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain [F3685]. … Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019.

    Synonyms: N8-GP, Turoctocog alfa pegol, N8-GP
  6. Drug

    Ouabain

    go.drugbank.com/drugs/DB01092
    Approved

    It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.

  7. Drug

    Berdazimer

    go.drugbank.com/drugs/DB18712
    Approved

    It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. … Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors.

  8. Drug

    Calcium glycerophosphate

    go.drugbank.com/drugs/DB11264
    Approved

    It is suggested that calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque [DB01373] and phosphate levels and direct interaction with dental mineral [A27153].

  9. Drug

    CT-011

    go.drugbank.com/drugs/DB05916
    Investigational

    It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.

  10. Drug

    Amylmetacresol

    go.drugbank.com/drugs/DB13908
    Approved

    Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections , . Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the ...

    Synonyms: 6-n-amyl-m-cresol, 6-n-pentyl-m-cresol