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Tofacitinib
go.drugbank.com/drugs/DB08895ApprovedInvestigationalTofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function. It is approved by the FDA for treatment of moderate to severe rheumatoid a...
Products: XELJANZ® XR 11 MG TABLETAS DE LIBERACIÓN MODIFICADAMavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigationalMavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is ...
Products: CAMZYOS® 2.5MG CAPSULAS DURAS DE LIBERACIÓN INMEDIATA.Biperiden
go.drugbank.com/drugs/DB00810ApprovedInvestigationalWithdrawnA muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapy...
Products: AKINETON® TABLETA DE LIBERACION PROLONGADADoxylamine
go.drugbank.com/drugs/DB00366ApprovedInvestigationalVet approvedHistamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Mixtures: Lil Drug Store Nighttime Cold and Flu, Lil Drug Store Nighttime Cold and FluProducts: Dg Health Sleep AidTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigationalDue to its SNRI activity, tramadol also has anxiolytic, antidepressant, and anti-shivering effects which are all frequently found as comorbidities with pain. … Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain.
Mixtures: ONEMER DT, DOLAC DUOProducts: TRATAMDOL TABLETAS DE LIBERACION PROLONGADA DE 100 MG, TRAMADOL CAPSULAS DE 50 MGDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigationalIn 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholineste...
Mixtures: EUTEBROL-DUOProducts: DONEPEZIL DR. REDDY'S, DOPECILO CLOHIDRATO DE DONEPECILO 10MGSorafenib
go.drugbank.com/drugs/DB00398ApprovedInvestigationalSorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approve...
Products: SORAFENIB DR. REDDYSPinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalPinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain...
Mixtures: DICETEL-DUO, DICETEL® DUOInternational brands: Alevian DuoGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigationalas mild cognitive impairment, cognitive impairment in schizophrenia and bipolar disorder, and autism; however, re-development of the drug for Alzheimer’s disease did not commence until the early 1990s due
Products: REMINYL ®ER CAPSULAS DE 8 MG, REMINYL ® ER CAPSULAS DE 16 MGSulbactam
go.drugbank.com/drugs/DB09324ApprovedInvestigationalSulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resis...
Mixtures: SULBACTER POWDER FOR SOLUTION FOR INJECTION or INFUSION 3g/vial, SULBACTER POWDER FOR SOLUTION FOR INJECTION or INFUSION 1.5g/vialProducts: PENTICLOX-DUO