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Larotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalOn April 10, 2025, the FDA granted full drug approval.[L52805] … of cell growth in tumors that overexpress Trk.
Products: VITRAKVI®CÁPSULAS DE 100MGVemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigational[A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann La Roche. … [A31269] It exerts its function by binding to the ATP-binding domain of the mutant BRAF.
Categories: combinations of sulfonamidesProducts: ZELBORAF ® TABLETAS LACADAS DE 240 MGMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalMetformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. … [A176173] Another well-known benefit of this drug is modest weight loss, making it an effective choice for obese patients type II diabetes.
International brands: Nu-MetforminMixtures: GALVUS® MET 50/500 COMPRIMIDOS RECUBIERTOS CON PELICULA, GALVUS® MET COMPRIMIDO RECUBIERTO CON PELICULA 50 MG/850 MGAlbuterol
go.drugbank.com/drugs/DB01001ApprovedInvestigationalVet approvedThis lead to the development of levalbuterol, the single R-isomer of salbutamol. … However, the high cost of levalbuterol compared to salbutamol has deterred wide-spread use of this enantiomerically pure version of the drug.
Mixtures: AXOL DUO, Combivent nebuliser solution in unit dose vialProducts: Nu-salbutamol - Tab 2mg, Nu-salbutamol - Tab 4mgMizolastine
go.drugbank.com/drugs/DB12523ApprovedMizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
Categories: Histamine H1 Antagonists, Non-SedatingProducts: MIZOLEN 10 MG TABLETAS DE LIBERACION PROLONGADAMemantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalInitially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … In December 2013, the G8 dementia summit concluded that dementia should be considered a global priority with the objective of developing a cure or a disease-modifying therapy by the year 2025 [L5953, F4366
Mixtures: EUTEBROL-DUOCategories: N-methyl-D-aspartate Receptor AntagonistIocetamic acid
go.drugbank.com/drugs/DB09403ApprovedIocetamic acid is a diagnostic aid (radiopaque medium)
Products: CHOLEBRINE 750 MG (MEDIO DE CONTRASTE RADIOLOGICO)BBIBP-CorV
go.drugbank.com/drugs/DB15807InvestigationalAs of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques[A219763].
Synonyms: Purified inactivated SARS-CoV-2 VaccinePotassium citrate
go.drugbank.com/drugs/DB09125ApprovedInvestigationalVet approvedPotassium Citrate is indicated also for the management of Hypocitraturic calcium oxalate nephrolithiasis. … Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste.
Mixtures: Calcium-magnesium With K & Zn and Vitamin D3, Cal-mag (one To One) With Potass & ZincProducts: U-ALKALIZER POTASSIUM CITRATE MIXTURE, UROCIT-K® 10 MEQ TABLETAS DE LIBERACION PROLONGADAPseudoephedrine
go.drugbank.com/drugs/DB00852ApprovedPseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823]
Mixtures: DESENFRIOL-ON GRAGEAS REPETABS, Hot Lemon Relief for Symptoms Of Cough, Cold and FluCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome