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Displaying results 411 - 420 of 10000 in total
  1. Drug

    Pasireotide

    go.drugbank.com/drugs/DB06663
    ApprovedInvestigational

    Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)
  2. Drug

    Ifosfamide

    go.drugbank.com/drugs/DB01181
    ApprovedInvestigational

    Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.

    Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSynonyms: 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
  3. Drug

    Prilocaine

    go.drugbank.com/drugs/DB00750
    ApprovedInvestigational

    A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

    Mixtures: Microvix L, Microvix LSynonyms: N-(2-Methylphenyl)-2-(propylamino)propanamide, 2-(Propylamino)-o-propionotoluidide
  4. Indication

    Liver iron concentration of at least 5 mg Fe per gram of dry weight

    go.drugbank.com/conditions/DBCOND0146507
    Drugs: Deferasirox
    Synonyms: Liver iron concentration of at least 5 mg Fe per gram of dry weight
  5. Drug

    Magnesium sulfate

    go.drugbank.com/drugs/DB00653
    ApprovedInvestigationalVet approved

    A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia.

    Mixtures: Finomel Peri Emulsion zur Infusion, ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKISynonyms: Magnesium sulfate (1:1)
  6. Drug

    Sus scrofa skin

    go.drugbank.com/drugs/DB10606
    Approved

    Sus scrofa skin or pelt is used in allergenic testing.

    Products: PiGe ll Real Skin Eye, PiGe ll Real Skin Neck Pack
  7. Target

    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

    go.drugbank.com/bio_entities/BE0009035
    TargetHumans

    Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing ...

    Polypeptides: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
  8. Drug

    Ammonium lactate

    go.drugbank.com/drugs/DB06768
    Approved

    Ammonium lactate is the ammonium salt of lactic acid.

    Mixtures: Ultravate X, Ultravate XProducts: Lac-Hydrin, Lac Hydrin Cream
  9. Drug

    PEG-Glucocerebrosidase

    go.drugbank.com/drugs/DB17660
    Investigational

    Synonyms: PEG-GC, PEG glucocerebrosidase
  10. Drug

    Dienogest

    go.drugbank.com/drugs/DB09123
    ApprovedInvestigational

    It is a derivative of 19-nortestosterone and has antiandrogenic properties. … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself.

    Mixtures: ACOTOL EX, Foxinette 0,03 mg/2 mg 21+7 - FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates