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Displaying results 411 - 420 of 10000 in total
  1. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. … [A7514] The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity.

    Mixtures: TRIUMEQ FILM COATED TABLET 50mg/600mg/300mgCategories: lamivudine and dolutegravir, dolutegravir and rilpivirine
  2. Drug

    Pentobarbital

    go.drugbank.com/drugs/DB00312
    ApprovedVet approved

    A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. … It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration.

    Categories: Hypnotics and SedativesProducts: Nova Rectal Sup 25mg, Novo-pentobarb 100mg
  3. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications … greater potency than the R-enantiomer, but is metabolized at a higher rate.

    Mixtures: TARKA 180MG/2MG, TARKA 180MG/2MGCategories: Verapamil and analogues, trandolapril and verapamil
  4. Drug

    Benzethonium

    go.drugbank.com/drugs/DB11125
    Approved

    There is evidence that benzethonium acts as a spermatocide but may cause vaginal irritation [A32304]. … It is shown to be effective in mediating its antimicrobial action against bacteria, fungi, mold and viruses.

    Mixtures: Tough Guy Hand Sanitizer Wipes Tough Guy, Gold Bond Pain and ItchCategories: Antiseptics and Disinfectants
  5. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [A275451] It is primarily indicated for "leucovorin rescue" to diminish the hematologic and mucosal toxicity of high-dose methotrexate therapy in osteosarcoma and to treat inadvertent overdoses of folic … [L56092, A257419] Unlike folic acid, leucovorin does not require the enzyme dihydrofolate reductase (DHFR) for activation, allowing it to function even when DHFR is inhibited by drugs like methotrexate

    Mixtures: NEO CROMATON BICOMPLESSOCategories: Enzymes and Coenzymes, Folic Acid and Derivatives
  6. Drug

    Timolol

    go.drugbank.com/drugs/DB00373
    ApprovedInvestigational

    [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension. … [L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978.

    Mixtures: AZARGA 10MG/ML+5MG/ML, AZARGA 10MG/ML + 5MG/MLCategories: Beta Blocking Agents, Non-Selective, and Thiazides, timolol and thiazides
  7. Drug

    Ephedrine

    go.drugbank.com/drugs/DB01364
    ApprovedInvestigational

    [L12972] Ephedrine and [phenylephrine] are still used to treat hypotension, but their use in other indications has decreased due to the development of more selective adrenergic agonists. … It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine

    Mixtures: NEO NAPACIN, NEO YEKASTHMACategories: Epinephrine and similars, Herbs and Natural Products
  8. Drug

    Iron

    go.drugbank.com/drugs/DB01592
    ApprovedInvestigational

    A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. … Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia.

    Mixtures: Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo, HERREX FOL TABLETAS RECUBIERTAS 100MG/400Categories: Diet, Food, and Nutrition, multivitamins and iron
  9. Drug

    Bacitracin

    go.drugbank.com/drugs/DB00626
    ApprovedInvestigationalVet approved

    [A181952] Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748] … [A181952] The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy.

    Mixtures: Bus and Classroom Yellow, Care Bus and Classroom YellowCategories: Amino Acids, Peptides, and Proteins
  10. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    Once administered, the R-enantiomer undergoes extensive interconversion to the S-enantiomer _in vivo_ by the activity of the alpha-methylacyl-CoA racemase. … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.

    Mixtures: IBUCOLD PLUS 100MG+15MG+1MG/5ML ŞURUP, 100 ML SISE, Period Pills by BiikayCategories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Ibuprofen and isomer